ARHGAP18 抗体
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北京 101111
Quick Overview for ARHGAP18 抗体 (ABIN7075417)
抗原
See all ARHGAP18 抗体适用
宿主
克隆类型
标记
应用范围
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交叉反应
- 人, 大鼠
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纯化方法
- Affinity purification
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免疫原
- Recombinant protein corresponding to Mouse ARHGAP18
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应用备注
- WB (H,M,R) 1:1000-1:1500, IHC/IF (M,R) 1:700-1:1400
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS, pH 7.4, 0.02 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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- ARHGAP18 (rho GTPase Activating Protein 18 (ARHGAP18))
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别名
- ARHGAP18
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背景
- Rho GTPase activating protein that suppresses F-actin polymerization by inhibiting Rho. Rho GTPase activating proteins act by converting Rho-type GTPases to an inactive GDP-bound state. Plays a key role in tissue tension and 3D tissue shape by regulating cortical actomyosin network formation. Acts downstream of YAP1 and inhibits actin polymerization, which in turn reduces nuclear localization of YAP1. Regulates cell shape, spreading, and migration.
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分子量
- 75 kDa
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基因ID
- 73910
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NCBI登录号
- NP_789807
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UniProt
- Q8K0Q5
抗原
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