ARHGAP17 抗体
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北京 101111
Quick Overview for ARHGAP17 抗体 (ABIN7075416)
抗原
See all ARHGAP17 抗体适用
宿主
克隆类型
标记
应用范围
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交叉反应
- 大鼠
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纯化方法
- Affinity purification
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免疫原
- Recombinant protein corresponding to Mouse ARHGAP17
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应用备注
- WB (M) 1:250-1:500, IHC/IF (R) 1:500-1:1500
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS, pH 7.4, 0.02 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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- ARHGAP17 (rho GTPase Activating Protein 17 (ARHGAP17))
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别名
- ARHGAP17
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背景
- ARHGAP17 is a Rho GTPase-activating protein involved in the maintenance of tight junction by regulating the activity of CDC42, thereby playing a central role in apical polarity of epithelial cells. It specifically acts as a GTPase activator for the CDC42 GTPase by converting it to an inactive GDP-bound state. RHGAP17 participates in the Ca(2+)-dependent regulation of exocytosis, possibly by catalyzing GTPase activity of Rho family proteins and by inducing the reorganization of the cortical actin filaments. Acts as a GTPase activator in vitro for RAC1.
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分子量
- 81 kDa
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基因ID
- 70497
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NCBI登录号
- NP_001116112
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UniProt
- Q3UIA2
抗原
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