RMND5A 抗体
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北京 101111
Quick Overview for RMND5A 抗体 (ABIN7075401)
抗原
See all RMND5A 抗体适用
宿主
克隆类型
标记
应用范围
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交叉反应
- 大鼠
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纯化方法
- Affinity purification
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免疫原
- Recombinant protein corresponding to Mouse RMND5A
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应用备注
- IHC/IF (M,R) 1:1500-1:3000/1:600-1:1200
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS, pH 7.4, 0.02 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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- RMND5A (Required For Meiotic Nuclear Division 5 Homolog A (RMND5A))
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别名
- RMND5A
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背景
- Core component of the CTLH E3 ubiquitin-protein ligase complex that selectively accepts ubiquitin from UBE2H and mediates ubiquitination and subsequent proteasomal degradation of the transcription factor HBP1. MAEA and RMND5A are both required for catalytic activity of the CTLH E3 ubiquitin-protein ligase complex. Catalytic activity of the complex is required for normal cell proliferation. The CTLH E3 ubiquitin-protein ligase complex is not required for the degradation of enzymes involved in gluconeogenesis, such as FBP1.
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基因ID
- 68477
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NCBI登录号
- NP_077250
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UniProt
- Q80YQ8
抗原
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