RANGRF 抗体
Our Local Distributor
北京 101111
Quick Overview for RANGRF 抗体 (ABIN7075362)
抗原
See all RANGRF 抗体适用
宿主
克隆类型
标记
应用范围
-
-
交叉反应
- 大鼠
-
纯化方法
- Affinity purification
-
免疫原
- KLH conjugated Synthetic peptide corresponding to Mouse MOG
-
-
-
-
应用备注
- IHC/IF (M,R) 1:1000-1:3000/1:500-1:1500
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
缓冲液
- PBS, pH 7.4, 0.02 % sodium azide
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- -20 °C
-
-
- RANGRF (RAN Guanine Nucleotide Release Factor (RANGRF))
-
别名
- MOG1
-
背景
- This gene encodes a protein that has been shown to function as a guanine nucleotide release factor in mouse and to regulate the expression and function of the Nav1.5 cardiac sodium channel in human. Alternative splicing results in multiple transcript variants. May regulate the intracellular trafficking of RAN. Promotes guanine nucleotide release from RAN and inhibits binding of new GTP by preventing the binding of the RAN guanine nucleotide exchange factor RCC1. Regulates the levels of GTP-bound RAN in the nucleus, and thereby plays a role in the regulation of RAN-dependent mitotic spindle dynamics (By similarity). Enhances the expression of SCN5A at the cell membrane in cardiomyocytes.
-
基因ID
- 57785
-
NCBI登录号
- NP_001272370
-
UniProt
- Q9JIB0
抗原
-