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RANGRF 抗体

This anti-RANGRF antibody is a 兔 多克隆 antibody detecting RANGRF in IHC 和 IF. Suitable for 小鼠 和 大鼠.
产品编号 ABIN7075362
发货至: 中国

Quick Overview for RANGRF 抗体 (ABIN7075362)

抗原

See all RANGRF 抗体
RANGRF (RAN Guanine Nucleotide Release Factor (RANGRF))

适用

  • 7
  • 4
  • 1
小鼠, 大鼠

宿主

  • 5
  • 1

克隆类型

  • 6
  • 1
多克隆

标记

  • 7
This RANGRF antibody is un-conjugated

应用范围

  • 6
  • 5
  • 4
  • 2
Immunohistochemistry (IHC), Immunofluorescence (IF)
  • 交叉反应

    大鼠

    纯化方法

    Affinity purification

    免疫原

    KLH conjugated Synthetic peptide corresponding to Mouse MOG
  • 应用备注

    IHC/IF (M,R) 1:1000-1:3000/1:500-1:1500

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS, pH 7.4, 0.02 % sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C
  • 抗原

    RANGRF (RAN Guanine Nucleotide Release Factor (RANGRF))

    别名

    MOG1

    背景

    This gene encodes a protein that has been shown to function as a guanine nucleotide release factor in mouse and to regulate the expression and function of the Nav1.5 cardiac sodium channel in human. Alternative splicing results in multiple transcript variants. May regulate the intracellular trafficking of RAN. Promotes guanine nucleotide release from RAN and inhibits binding of new GTP by preventing the binding of the RAN guanine nucleotide exchange factor RCC1. Regulates the levels of GTP-bound RAN in the nucleus, and thereby plays a role in the regulation of RAN-dependent mitotic spindle dynamics (By similarity). Enhances the expression of SCN5A at the cell membrane in cardiomyocytes.

    基因ID

    57785

    NCBI登录号

    NP_001272370

    UniProt

    Q9JIB0
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