电话:
+86 (0512) 65829739
传真:
+86 (010) 6788 5057
电子邮件:
orders@antibodies-online.cn

PTPN12 抗体

This anti-PTPN12 antibody is a 兔 多克隆 antibody detecting PTPN12 in WB, IHC 和 IF. Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN7075292
发货至: 中国

Quick Overview for PTPN12 抗体 (ABIN7075292)

抗原

See all PTPN12 抗体
PTPN12 (Protein Tyrosine Phosphatase G1 (PTPN12))

适用

  • 58
  • 9
  • 7
  • 4
  • 4
  • 3
  • 3
  • 3
  • 1
  • 1
人, 小鼠, 大鼠

宿主

  • 53
  • 5

克隆类型

  • 54
  • 4
多克隆

标记

  • 34
  • 3
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This PTPN12 antibody is un-conjugated

应用范围

  • 46
  • 15
  • 14
  • 13
  • 13
  • 11
  • 8
  • 6
  • 5
  • 3
  • 3
  • 1
Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
  • 交叉反应

    人, 大鼠

    纯化方法

    Affinity purification

    免疫原

    KLH conjugated Synthetic peptide corresponding to Mouse PTPN12
  • 应用备注

    WB (H,M,R) 1: 500-1: 800, IHC/IF (H,M,R) 1:1000-1:3000/1:500-1:2000

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS, pH 7.4, 0.02 % sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C
  • 抗原

    PTPN12 (Protein Tyrosine Phosphatase G1 (PTPN12))

    别名

    PTPN12

    背景

    The PTPN12 is a member of the protein tyrosine phosphatase (PTP) family. PTPs are signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains a C-terminal PEST motif, which serves as a protein-protein interaction domain, and may regulate protein intracellular half-life. This PTP was found to bind and dephosphorylate the product of the oncogene c-ABL and thus may play a role in oncogenesis. The PTP was also shown to interact with, and dephosphorylate, various products related to cytoskeletal structure and cell adhesion. This suggests it has a regulatory role in controlling cell shape and mobility.

    分子量

    110 kDa

    基因ID

    19248

    NCBI登录号

    NP_035333

    UniProt

    P35831
You are here:
Chat with us!