PTGDR 抗体
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北京 101111
Quick Overview for PTGDR 抗体 (ABIN7075206)
抗原
See all PTGDR 抗体适用
宿主
克隆类型
标记
应用范围
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交叉反应
- 大鼠
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纯化方法
- Affinity purification
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免疫原
- KLH conjugated Synthetic peptide corresponding to Mouse Prostaglandin D2 Receptor
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应用备注
- WB (M,R) 1:1000-1:2000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS, pH 7.4, 0.02 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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- PTGDR (Prostaglandin D2 Receptor (PTGDR))
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别名
- Prostaglandin D2 Receptor
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背景
- Receptor for prostaglandin D2 (PGD2). The activity of this receptor is mainly mediated by G(s) proteins that stimulate adenylate cyclase, resulting in an elevation of intracellular cAMP. A mobilization of calcium is also observed, but without formation of inositol 1,4,5-trisphosphate . Involved in PLA2G3-dependent maturation of mast cells. PLA2G3 is secreted by immature mast cells and acts on nearby fibroblasts upstream to PTDGS to synthesize PGD2, which in turn promotes mast cell maturation and degranulation via PTGDR.
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分子量
- 50 kDa
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基因ID
- 19214
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NCBI登录号
- NP_032988
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UniProt
- P70263
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途径
- Thromboxane A2 Receptor Signaling
抗原
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