PLSCR3 抗体
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北京 101111
Quick Overview for PLSCR3 抗体 (ABIN7075071)
抗原
See all PLSCR3 抗体适用
宿主
克隆类型
标记
应用范围
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交叉反应
- 大鼠
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纯化方法
- Affinity purification
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免疫原
- Recombinant protein corresponding to Mouse PLSCR3
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应用备注
- WB (M,R) 1: 500-1:1000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS, pH 7.4, 0.02 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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- PLSCR3 (phospholipid Scramblase 3 (PLSCR3))
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别名
- PLSCR3
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背景
- PLSCR3 (phospholipid scramblase 3) may mediate accelerated ATP-independent bidirectional transbilayer migration of phospholipids upon binding calcium ions that results in a loss of phospholipid asymmetry in the plasma membrane. May play a central role in the initiation of fibrin clot formation, in the activation of mast cells and in the recognition of apoptotic and injured cells by the reticuloendothelial system. Members of this family, PLS1 and PLS3 are both substrates of Protein kinase C (PKC) delta and are phosphorylated by PKC-delta during apoptosis. PKC-delta translocates to mitochondria during apoptosis and phosphorylates PLS3. Overexpression of PLS3 in the HEK293 cells enhanced apoptosis induced by UV-irradiation.
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分子量
- 32 kDa
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基因ID
- 70310
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NCBI登录号
- NP_001161969
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UniProt
- Q9JIZ9
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途径
- Cellular Response to Molecule of Bacterial Origin, Carbohydrate Homeostasis
抗原
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