NOS1AP 抗体
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北京 101111
Quick Overview for NOS1AP 抗体 (ABIN7074844)
抗原
See all NOS1AP 抗体适用
宿主
克隆类型
标记
应用范围
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交叉反应
- 人, 大鼠
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纯化方法
- Affinity purification
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免疫原
- Recombinant protein corresponding to Mouse CAPON/NOS1AP
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应用备注
- WB (H,M,R) 1:500-1:1000, IHC/IF (M,R) 1:2000-1:4000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS, pH 7.4, 0.02 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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- NOS1AP (Nitric Oxide Synthase 1 (Neuronal) Adaptor Protein (NOS1AP))
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别名
- CAPON/NOS1AP
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背景
- CAPON (carboxy-terminal PDZ ligand of nNOS) selectively binds within the 100 amino acid PDZ domain of the neuronal nitric oxide synthase (nNOS), but not to endothelial NOS or inducible NOS, and sequesters nNOS in the cytosol. Biosynthesis of the neurotransmitter nitric oxide (NO) requires the association of nNOS with various synaptic proteins, including syntrophin, postsynaptic density (PSD)95 and PSD93 through a scaffolding PDZ domain. These proteins facilitate the transport of nNOS to the plasma membrane, where it is catalytically activated by NMDA-receptor mediated calcium channels.
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分子量
- 56 kDa
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基因ID
- 70729
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NCBI登录号
- NP_001103455
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UniProt
- Q9D3A8
抗原
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