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MYLK3 抗体

This anti-MYLK3 antibody is a 兔 多克隆 antibody detecting MYLK3 in IHC 和 IF. Suitable for 小鼠 和 大鼠.
产品编号 ABIN7074736
发货至: 中国

Quick Overview for MYLK3 抗体 (ABIN7074736)

抗原

See all MYLK3 抗体
MYLK3 (Myosin Light Chain Kinase 3 (MYLK3))

适用

  • 47
  • 35
  • 17
  • 1
  • 1
  • 1
  • 1
小鼠, 大鼠

宿主

  • 56

克隆类型

  • 56
多克隆

标记

  • 21
  • 4
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  • 4
  • 3
  • 3
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
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This MYLK3 antibody is un-conjugated

应用范围

  • 47
  • 24
  • 21
  • 5
  • 4
  • 3
  • 1
  • 1
Immunohistochemistry (IHC), Immunofluorescence (IF)
  • 交叉反应

    大鼠

    纯化方法

    Affinity purification

    免疫原

    Recombinant protein corresponding to Mouse MYLK3/MLCK
  • 应用备注

    IHC/IF (M,R) 1:600-1:1200

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS, pH 7.4, 0.02 % sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C
  • 抗原

    MYLK3 (Myosin Light Chain Kinase 3 (MYLK3))

    别名

    MYLK3/MLCK

    背景

    The Ca2+/calmodulin-dependent protein kinases (CaM kinases) are a structurally related subfamily of serine/threonine kinases that includes CaMKI, CaMKII, CaMKIV and Myosin light chain kinases (MYLKs, also designated MLCKs). The MYLK kinases phosphorylate Myosin regulatory light chains to catalyze Myosin interaction with Actin filaments, resulting in contractile activity. MYLK3 (Myosin light chain kinase 3) is a 795 amino acid cardiac-specific protein that contains one protein kinase domain and belongs to the protein kinase superfamily. Like other MYLK kinases, MYLK3 is thought to play a role in smooth muscle contraction, specifically using magnesium as a cofactor to catalyze the ATP-dependent phosphorylation of Myosin light chain proteins. Additionally, MYLK3 may regulate sarcomere assembly in heart tissue, possibly mediating proper heart function.

    基因ID

    213435

    NCBI登录号

    NP_001284541

    UniProt

    Q3UIZ8

    途径

    Regulation of Muscle Cell Differentiation
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