MECOM 抗体
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北京 101111
Quick Overview for MECOM 抗体 (ABIN7074575)
抗原
See all MECOM 抗体适用
宿主
克隆类型
标记
应用范围
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交叉反应
- 人, 大鼠
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纯化方法
- Affinity purification
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免疫原
- KLH conjugated Synthetic peptide corresponding to Mouse EVI1
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应用备注
- WB (H,M) 1:500-1:1000, IHC/IF (M,R) 1:2000-1:4000/1:700-1:1400
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS, pH 7.4, 0.02 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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- MECOM (MDS1 and EVI1 Complex Locus (MECOM))
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别名
- EVI1
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背景
- The protein encoded by this gene is a transcriptional regulator and oncoprotein that may be involved in hematopoiesis, apoptosis, development, and cell differentiation and proliferation. The encoded protein can interact with CTBP1, SMAD3, CREBBP, KAT2B, MAPK8, and MAPK9. This gene can undergo translocation with the AML1 gene, resulting in overexpression of this gene and the onset of leukemia. Several transcript variants encoding a few different isoforms have been found for this gene.
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分子量
- 118 kDa
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基因ID
- 14013
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NCBI登录号
- NP_067417
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UniProt
- P14404
抗原
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