KIF5B 抗体
Quick Overview for KIF5B 抗体 (ABIN7074440)
抗原
See all KIF5B 抗体适用
宿主
克隆类型
标记
应用范围
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交叉反应
- 大鼠
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纯化方法
- Affinity purification
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免疫原
- KLH conjugated Synthetic peptide corresponding to Mouse KIF5B
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应用备注
- WB (M,R) 1:2000-1:4000, IHC/IF (M,R) 1:500-1:1000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS, pH 7.4, 0.02 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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- KIF5B (Kinesin Family Member 5B (KIF5B))
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别名
- KIF5B
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背景
- Microtubule-dependent motor required for normal distribution of mitochondria and lysosomes. May be involved in the mechanisms of growth arrest induced by exposure to DNA-damaging drugs or by cellular senescence . Can induce formation of neurite-like membrane protrusions in non-neuronal cells in a ZFYVE27-dependent manner . Regulates centrosome and nuclear positioning during mitotic entry. During the G2 phase of the cell cycle in a BICD2-dependent manner, antagonizes dynein function and drives the separation of nuclei and centrosomes. Required for anterograde axonal transportation of MAPK8IP3/JIP3 which is essential for MAPK8IP3/JIP3 function in axon elongation .
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分子量
- 130 kDa
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基因ID
- 16573
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NCBI登录号
- NP_032474
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UniProt
- Q61768
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途径
- Peptide Hormone Metabolism, Ribonucleoprotein Complex Subunit Organization
抗原
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