ISR-alpha 抗体
Quick Overview for ISR-alpha 抗体 (ABIN7074298)
抗原
See all ISR-alpha 抗体适用
宿主
克隆类型
标记
应用范围
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交叉反应
- 人, 大鼠
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纯化方法
- Affinity purification
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免疫原
- KLH conjugated Synthetic peptide corresponding to Mouse Insulin Receptor alpha
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anti-Insulin Receptor alpha (ISR-alpha) (AA 701-760) antibody
ISR-alpha 适用: 人, 大鼠 IF (cc), IF (p), WB, FACS, IHC (p), ELISA, IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Insulin Receptor alpha (ISR-alpha) (AA 51-150) antibodyISR-alpha 适用: 人, 大鼠 IF (cc), IF (p), IHC (p), ELISA, IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Insulin Receptor alpha (ISR-alpha) antibodyISR-alpha 适用: 人 Crys 宿主: 兔 Chimeric Fab 83-7 unconjugated Recombinant Antibody
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应用备注
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IHC: 1: 3000-1: 6000
Human, Mouse, Rat: Human, Mouse, Rat
Positive Tissue: endometrial cancer, esophagus cancer, uterus,small intestine -
限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS, pH 7.4, 0.02 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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- ISR-alpha (Insulin Receptor alpha (ISR-alpha))
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别名
- Insulin Receptor alpha
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背景
- This gene encodes a member of the receptor tyrosine kinase family of proteins. The encoded preproprotein is proteolytically processed to generate alpha and beta subunits that form a heterotetrameric receptor. Binding of insulin or other ligands to this receptor activates the insulin signaling pathway, which regulates glucose uptake and release, as well as the synthesis and storage of carbohydrates, lipids and protein. Mutations in this gene underlie the inherited severe insulin resistance syndromes including type A insulin resistance syndrome, Donohue syndrome and Rabson-Mendenhall syndrome. Alternative splicing results in multiple transcript variants.
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基因ID
- 16337
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UniProt
- P15208
抗原
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