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GTF2B 抗体

This anti-GTF2B antibody is a 兔 多克隆 antibody detecting GTF2B in WB, IHC 和 IF. Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN7074034
发货至: 中国

Quick Overview for GTF2B 抗体 (ABIN7074034)

抗原

See all GTF2B 抗体
GTF2B (General Transcription Factor IIB (GTF2B))

适用

  • 80
  • 30
  • 15
  • 13
  • 9
  • 8
  • 8
  • 8
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  • 7
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  • 1
人, 小鼠, 大鼠

宿主

  • 64
  • 16

克隆类型

  • 64
  • 16
多克隆

标记

  • 46
  • 5
  • 4
  • 3
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This GTF2B antibody is un-conjugated

应用范围

  • 60
  • 27
  • 13
  • 13
  • 13
  • 12
  • 7
  • 7
  • 6
  • 5
  • 3
  • 2
  • 2
  • 1
  • 1
  • 1
Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
  • 交叉反应

    人, 大鼠

    纯化方法

    Affinity purification

    免疫原

    Recombinant protein corresponding to Mouse TFIIB
  • 应用备注

    WB (H,M,R) 1: 500-1: 1000, IHC/IF (H,M,R) 1:500-1:1500/1:500-1:1000

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS, pH 7.4, 0.02 % sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C
  • 抗原

    GTF2B (General Transcription Factor IIB (GTF2B))

    别名

    TFIIB

    背景

    General transcription factor that plays a role in transcription initiation by RNA polymerase II (Pol II). Involved in the pre-initiation complex (PIC) formation and Pol II recruitment at promoter DNA .Together with the TATA box-bound TBP forms the core initiation complex and provides a bridge between TBP and the Pol II-TFIIF complex .Released from the PIC early following the onset of transcription during the initiation and elongation transition and reassociates with TBP during the next transcription cycle . Associates with chromatin to core promoter- specific regions .Binds to two distinct DNA core promoter consensus sequence elements in a TBP-independent manner,Modulates transcription start site selection . Exhibits also autoacetyltransferase activity that contributes to the activated transcription .

    分子量

    35 kDa

    基因ID

    229906

    NCBI登录号

    NP_663521

    UniProt

    P62915
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