FOXL2 抗体
Quick Overview for FOXL2 抗体 (ABIN7073971)
抗原
See all FOXL2 抗体适用
宿主
克隆类型
标记
应用范围
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纯化方法
- Affinity purification
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免疫原
- Recombinant protein corresponding to Mouse FOXL2
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应用备注
- IHC/IF (M) 1:3000-1:6000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS, pH 7.4, 0.02 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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- FOXL2 (Forkhead Box L2 (FOXL2))
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别名
- FOXL2
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背景
- Transcriptional regulator. Critical factor essential for ovary differentiation and maintenance, and repression of the genetic program for somatic testis determination. Prevents trans-differentiation of ovary to testis throught transcriptional repression of the Sertoli cell-promoting gene SOX9 (By similarity). Has apoptotic activity in ovarian cells. Suppresses ESR1-mediated transcription of PTGS2/COX2 stimulated by tamoxifen (By similarity). Is a regulator of CYP19 expression (By similarity). Participates in SMAD3-dependent transcription of FST via the intronic SMAD-binding element (By similarity). Is a transcriptional repressor of STAR.
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基因ID
- 26927
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UniProt
- O88470
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途径
- Nuclear Hormone Receptor Binding, Positive Regulation of Endopeptidase Activity
抗原
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