Foxk1 抗体
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北京 101111
Quick Overview for Foxk1 抗体 (ABIN7073970)
抗原
See all Foxk1 抗体适用
宿主
克隆类型
标记
应用范围
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交叉反应
- 人, 大鼠
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纯化方法
- Affinity purification
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免疫原
- Recombinant protein corresponding to Mouse FOXK1/MNF
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应用备注
- WB (H) 1:500-1:1000, IHC/IF (H,M,R) 1:1000-1:2000/1:650-1:1300
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS, pH 7.4, 0.02 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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- Foxk1 (Forkhead Box K1 (Foxk1))
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别名
- FOXK1/MNF
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背景
- The FOX family of transcription factors share a common DIUA binding domain termed a winged-helix or forkhead domain. Many FOX proteins play important roles in development, metabolism, cancer and aging. In skeletal muscles, undifferentiated myogenic stem cells (satellite cells) can mobilize to regenerate myofibers in response to injury. FOXK1 is expressed in these cells and regulates cell cycle progression through an interaction with its downstream target the cyclin-dependent kinase inhibitor p21 (CIP). Loss of FOXK1 in mice results in growth retardation and a severe impairment in skeletal muscle regeneration following injury. FOXK1 also shows expression in immature tissues of brain, eye, heart, lung and thymus.
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分子量
- 97 kDa
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基因ID
- 17425
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NCBI登录号
- NP_951031
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UniProt
- P42128
抗原
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