FOSB 抗体
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北京 101111
Quick Overview for FOSB 抗体 (ABIN7073925)
抗原
See all FOSB 抗体适用
宿主
克隆类型
标记
应用范围
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交叉反应
- 人, 大鼠
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纯化方法
- Affinity purification
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免疫原
- KLH conjugated Synthetic peptide corresponding to Mouse FOSB
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应用备注
- WB (H,M,R) 1:1000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS, pH 7.4, 0.02 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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- FOSB (FBJ Murine Osteosarcoma Viral Oncogene Homolog B (FOSB))
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别名
- Fos B
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背景
- The FOS gene family consists of 4 members: FOS, FOSB, FOSL1, and FOSL2. These genes encode leucine zipperproteins that can dimerize with proteins of the JUN family (e.g., c-Jun, JunD), thereby forming thetranscription factor complex AP-1. As such, the FOS proteins have been implicated as regulators of cell proliferation, differentiation, and transformation. FosB and its truncated splice variants, ΔFosB and further truncated Δ2ΔFosB, are all involved in osteosclerosis, although Δ2ΔFosB lacks a knowntransactivation domain, in turn preventing it from affecting transcription through the AP-1 complex.
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分子量
- 36 kDa
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基因ID
- 14282
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NCBI登录号
- NP_032062
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UniProt
- P13346
抗原
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