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eRF3/GSPT1 抗体

The 兔 多克隆 anti-eRF3/GSPT1 antibody is suitable to detect eRF3/GSPT1 in samples from 人, 小鼠 和 大鼠. It has been validated for WB.
产品编号 ABIN7073859
发货至: 中国
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Quick Overview for eRF3/GSPT1 抗体 (ABIN7073859)

抗原

eRF3/GSPT1

适用

  • 2
  • 2
  • 2
  • 1
人, 小鼠, 大鼠

宿主

  • 2

克隆类型

  • 1
  • 1
多克隆

标记

  • 2
非结合性

应用范围

  • 2
  • 1
  • 1
Western Blotting (WB)
  • 交叉反应

    人, 大鼠

    纯化方法

    Affinity purification

    免疫原

    Recombinant protein corresponding to Mouse eRF3/GSPT1
  • 应用备注

    WB (H,M,R) 1:500-1:1000

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS, pH 7.4, 0.02 % sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C
  • 抗原

    eRF3/GSPT1

    背景

    ERF3a is a 499 amino acid protein that belongs to the GTP-binding elongation factor family and is involved in the regulation of cell growth, specifically via control of translation termination. Human eRF3a shares 94 % sequence identity with its mouse counterpart, suggesting a conserved function between species. The gene encoding eRF3a maps to human chromosome 16, which encodes over 900 genes and comprises nearly 3 % of the human genome. The GAN gene is located on chromosome 16 and, with mutation, may lead to giant axonal neuropathy, a nervous system disorder characterized by increasing malfunction with growth.

    分子量

    72 kDa

    基因ID

    14852

    NCBI登录号

    NP_001123480

    UniProt

    Q8R050
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