eRF3/GSPT1 抗体
This anti- antibody is a 兔 多克隆 antibody detecting in WB. Suitable for 人, 小鼠 和 大鼠.
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Quick Overview for eRF3/GSPT1 抗体 (ABIN7073859)
抗原
eRF3/GSPT1
适用
人, 小鼠, 大鼠
宿主
兔
克隆类型
多克隆
标记
非结合性
应用范围
Western Blotting (WB)
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交叉反应
- 人, 大鼠
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纯化方法
- Affinity purification
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免疫原
- Recombinant protein corresponding to Mouse eRF3/GSPT1
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应用备注
- WB (H,M,R) 1:500-1:1000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS, pH 7.4, 0.02 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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- eRF3/GSPT1
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背景
- ERF3a is a 499 amino acid protein that belongs to the GTP-binding elongation factor family and is involved in the regulation of cell growth, specifically via control of translation termination. Human eRF3a shares 94 % sequence identity with its mouse counterpart, suggesting a conserved function between species. The gene encoding eRF3a maps to human chromosome 16, which encodes over 900 genes and comprises nearly 3 % of the human genome. The GAN gene is located on chromosome 16 and, with mutation, may lead to giant axonal neuropathy, a nervous system disorder characterized by increasing malfunction with growth.
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分子量
- 72 kDa
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基因ID
- 14852
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NCBI登录号
- NP_001123480
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UniProt
- Q8R050
抗原
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