DOCK2 抗体
Our Local Distributor
北京 101111
Quick Overview for DOCK2 抗体 (ABIN7073706)
抗原
See all DOCK2 抗体适用
宿主
克隆类型
标记
应用范围
-
-
交叉反应
- 人, 大鼠
-
纯化方法
- Affinity purification
-
免疫原
- Recombinant protein corresponding to Mouse DOCK2
-
-
-
-
应用备注
- WB (H,M,R) 1:500-1:1000
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
缓冲液
- PBS, pH 7.4, 0.02 % sodium azide
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- -20 °C
-
-
- DOCK2 (Dedicator of Cytokinesis 2 (DOCK2))
-
别名
- DOCK2
-
背景
- The DOCK2 gene encodes dedicator of cytokinesis 2 (DOCK 2), a hematopoietic cell-specific CDM family protein that is indispensable for lymphocyte chemotaxis. DOCK 2 participates in the cytoskeletal rearrangements that are required for lymphocyte migration in response of chemokines. DOCK 2 may also participate in IL-2 transcriptional activation through the activation of Rac 2. DOCK 2 contains one DHR-1 (CZH-1) domain, one DHR-2 (CZH-2) domain and one SH3 domain. The DHR-2 domain is a putative GEF activity mediator. The DOCK 2 protein also co-localizes with F-Actin, and demonstrates expression in several human tissues, with the highest levels observed in peripheral blood leukocytes, thymus, spleen and liver.
-
分子量
- 220 kDa
-
基因ID
- 94176
-
NCBI登录号
- NP_203538
-
UniProt
- Q8C3J5
抗原
-