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- 抗原 See all CYB561 抗体
- CYB561 (Cytochrome B-561 (CYB561))
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适用
- 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This CYB561 antibody is un-conjugated
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应用范围
- Immunofluorescence (IF), Immunohistochemistry (IHC)
- 交叉反应
- 大鼠
- 纯化方法
- Affinity purification
- 免疫原
- Recombinant protein corresponding to Mouse Pyruvate Dehydrogenase E2
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anti-Cytochrome B-561 (CYB561) antibody
CYB561 适用: 人, 小鼠 WB, IP, ICC 宿主: 小鼠 Monoclonal unconjugated
anti-Cytochrome B-561 (CYB561) (AA 144-193) antibodyCYB561 适用: 人, 小鼠, 大鼠, 豚鼠, Cow, 犬, 马, 兔, 绵羊, Pig, Hamster WB 宿主: 兔 Polyclonal unconjugated
anti-Cytochrome B-561 (CYB561) (C-Term) antibodyCYB561 适用: 人, 小鼠, 大鼠, 猴, 非洲爪蟾 WB 宿主: 兔 Polyclonal unconjugated
anti-Cytochrome B-561 (CYB561) (AA 72-121) antibodyCYB561 适用: 人, 豚鼠, 猴, Bat WB 宿主: 兔 Polyclonal unconjugated
anti-Cytochrome B-561 (CYB561) antibodyCYB561 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Cytochrome B-561 (CYB561) (Middle Region) antibodyCYB561 适用: 人, 小鼠, 大鼠, 豚鼠, Cow, 犬, 马, 兔, 绵羊, Pig WB 宿主: 兔 Polyclonal unconjugated
anti-Cytochrome B-561 (CYB561) (N-Term) antibodyCYB561 适用: 人, 小鼠, 大鼠, 豚鼠, Cow, 犬, 马, 兔, 绵羊 WB 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- IHC/IF (R) 1:500-1:1000
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- PBS, pH 7.4, 0.02 % sodium azide
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
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- 抗原
- CYB561 (Cytochrome B-561 (CYB561))
- 别名
- Pyruvate Dehydrogenase E2 (CYB561 产品)
- 别名
- CYB561A1 antibody, FRRS2 antibody, ECK1410 antibody, JW5224 antibody, MGC69260 antibody, zgc:193680 antibody, zgc:193701 antibody, ACYB-1 antibody, MBB18.18 antibody, MBB18_18 antibody, cytochrome B561-1 antibody, xcyt antibody, cytochrome b561 antibody, cytochrome b-561 antibody, cytochrome B561-1 antibody, cytochrome b561 L homeolog antibody, CYB561 antibody, cytb561 antibody, cybB antibody, LOC5576849 antibody, LOC5576850 antibody, Cyb561 antibody, cyb561 antibody, CYB-1 antibody, cyb561.L antibody, LOC100347599 antibody
- 背景
- This gene encodes component E2 of the multi-enzyme pyruvate dehydrogenase complex (PDC). PDC resides in the inner mitochondrial membrane and catalyzes the conversion of pyruvate to acetyl coenzyme A. The protein product of this gene, dihydrolipoamide acetyltransferase, accepts acetyl groups formed by the oxidative decarboxylation of pyruvate and transfers them to coenzyme A. Dihydrolipoamide acetyltransferase is the antigen for antimitochondrial antibodies. These autoantibodies are present in nearly 95 % of patients with the autoimmune liver disease primary biliary cirrhosis (PBC). In PBC, activated T lymphocytes attack and destroy epithelial cells in the bile duct where this protein is abnormally distributed and overexpressed. PBC enventually leads to cirrhosis and liver failure.
- 基因ID
- 235339
- UniProt
- Q8BMF4
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