CYB561 抗体
Quick Overview for CYB561 抗体 (ABIN7073661)
抗原
See all CYB561 抗体适用
宿主
克隆类型
标记
应用范围
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交叉反应
- 大鼠
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纯化方法
- Affinity purification
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免疫原
- Recombinant protein corresponding to Mouse Pyruvate Dehydrogenase E2
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anti-Cytochrome B-561 (CYB561) antibody
CYB561 适用: 人, 小鼠 WB, IP, ICC 宿主: 小鼠 Monoclonal unconjugated
anti-Cytochrome B-561 (CYB561) (AA 72-121) antibodyCYB561 适用: 人, 豚鼠, 猴, Bat WB 宿主: 兔 Polyclonal unconjugated
anti-Cytochrome B-561 (CYB561) (AA 144-193) antibodyCYB561 适用: 人, 小鼠, 大鼠, 豚鼠, Cow, 犬, 马, 兔, 绵羊, Pig, Hamster WB 宿主: 兔 Polyclonal unconjugated
anti-Cytochrome B-561 (CYB561) (C-Term) antibodyCYB561 适用: 人, 小鼠, 大鼠, 猴, 非洲爪蟾 WB 宿主: 兔 Polyclonal unconjugated
anti-Cytochrome B-561 (CYB561) (Middle Region) antibodyCYB561 适用: 人, 小鼠, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Cytochrome B-561 (CYB561) (N-Term) antibodyCYB561 适用: 人, 小鼠, 大鼠, 豚鼠, Cow, 犬, 马, 兔, 绵羊 WB 宿主: 兔 Polyclonal unconjugated
anti-Cytochrome B-561 (CYB561) (Middle Region) antibodyCYB561 适用: 人, 小鼠, 大鼠, 豚鼠, Cow, 犬, 马, 兔, 绵羊, Pig WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- IHC/IF (R) 1:500-1:1000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS, pH 7.4, 0.02 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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- CYB561 (Cytochrome B-561 (CYB561))
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别名
- Pyruvate Dehydrogenase E2
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背景
- This gene encodes component E2 of the multi-enzyme pyruvate dehydrogenase complex (PDC). PDC resides in the inner mitochondrial membrane and catalyzes the conversion of pyruvate to acetyl coenzyme A. The protein product of this gene, dihydrolipoamide acetyltransferase, accepts acetyl groups formed by the oxidative decarboxylation of pyruvate and transfers them to coenzyme A. Dihydrolipoamide acetyltransferase is the antigen for antimitochondrial antibodies. These autoantibodies are present in nearly 95 % of patients with the autoimmune liver disease primary biliary cirrhosis (PBC). In PBC, activated T lymphocytes attack and destroy epithelial cells in the bile duct where this protein is abnormally distributed and overexpressed. PBC enventually leads to cirrhosis and liver failure.
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基因ID
- 235339
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UniProt
- Q8BMF4
抗原
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