CDKN2C 抗体
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北京 101111
Quick Overview for CDKN2C 抗体 (ABIN7073645)
抗原
See all CDKN2C 抗体适用
宿主
克隆类型
标记
应用范围
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交叉反应
- 大鼠
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纯化方法
- Affinity purification
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免疫原
- Recombinant protein corresponding to Mouse CDKN2C
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应用备注
- WB (M,R) 1: 500-1: 1000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS, pH 7.4, 0.02 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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- CDKN2C (Cyclin-Dependent Kinase Inhibitor 2C (p18, Inhibits CDK4) (CDKN2C))
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别名
- p18 INK4c
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背景
- Cyclin-dependent kinase 4 inhibitor C is an enzyme encoded by the CDKN2C gene. The protein is a member of the INK4 family of cyclin-dependent kinase inhibitors. This protein has been shown to interact with CDK4 or CDK6, and prevent the activation of the CDK kinases, thus function as a cell growth regulator that controls cell cycle G1 progression. Ectopic expression of this gene was shown to suppress the growth of human cells in a manner that appears to correlate with the presence of a wild-type RB1 function. Studies in the knockout mice suggested the roles of this gene in regulating spermatogenesis, as well as in suppressing tumorigenesis. Two alternatively spliced transcript variants of this gene, which encode an identical protein, have been reported.
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分子量
- 18 kDa
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基因ID
- 12580
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NCBI登录号
- NP_001288297
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UniProt
- Q60772
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途径
- Cell Division Cycle, Mitotic G1-G1/S Phases
抗原
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