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CD3 抗体

This anti-CD3 antibody is a 兔 多克隆 antibody detecting CD3 in IHC, IF 和 WB. Suitable for 人, 小鼠 和 大鼠. This Primary Antibody has been cited in 3+ publications.
产品编号 ABIN7073386
发货至: 中国

Quick Overview for CD3 抗体 (ABIN7073386)

抗原

See all CD3 抗体
CD3

适用

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人, 小鼠, 大鼠

宿主

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克隆类型

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多克隆

标记

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This CD3 antibody is un-conjugated

应用范围

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Immunohistochemistry (IHC), Immunofluorescence (IF), Western Blotting (WB)
  • 交叉反应

    人, 大鼠

    纯化方法

    Affinity purification

    免疫原

    KLH conjugated Synthetic peptide corresponding to Mouse CD3
  • 应用备注

    WB (H,M,R) 1:500-1:1000, IHC/IF (H,M,R) 1:250-1:1000/1:250-1:1000

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS, pH 7.4, 0.02 % sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C
  • Feng, Yang, Luo, Sun, Lv, Wan, Guan, Xiao, Liu, Li, Dong, Yang: "The kinase PDK1 regulates regulatory T cell survival via controlling redox homeostasis." in: Theranostics, Vol. 11, Issue 19, pp. 9503-9518, (2022) (PubMed).

    He, Wang, Lu, Yang, Xue, Zhu, Zhang, Fan: "Single-cell RNA sequencing reveals heterogeneous tumor and immune cell populations in early-stage lung adenocarcinomas harboring EGFR mutations." in: Oncogene, Vol. 40, Issue 2, pp. 355-368, (2021) (PubMed).

    Chen, Gu, Jia, Liu, Liu, Liu, Xu, Lin, Lin, Liu, Chen, Xu, Yuan, Zhang, Zhang, Xiao, Gu: "Optimization Strategy for Generating Gene-edited Tibet Minipigs by Synchronized Oestrus and Cytoplasmic Microinjection." in: International journal of biological sciences, Vol. 15, Issue 12, pp. 2719-2732, (2020) (PubMed).

  • 抗原

    CD3

    别名

    CD3

    背景

    The protein encoded by this gene is the CD3-epsilon polypeptide, which together with CD3-gamma, -delta and -zeta, and the T-cell receptor alpha/beta and gamma/delta heterodimers, forms the T cell receptor-CD3 complex. This complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. The genes encoding the epsilon, gamma and delta polypeptides are located in the same cluster on chromosome 11. The epsilon polypeptide plays an essential role in T-cell development.

    分子量

    21 kDa

    基因ID

    12501

    NCBI登录号

    NP_031674

    UniProt

    P22646

    途径

    TCR Signaling, Ubiquitin Proteasome Pathway
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