Basonuclin 1 抗体
Our Local Distributor
北京 101111
Quick Overview for Basonuclin 1 抗体 (ABIN7073188)
抗原
See all Basonuclin 1 (BNC1) 抗体适用
宿主
克隆类型
标记
应用范围
-
-
交叉反应
- 人, 大鼠
-
纯化方法
- Affinity purification
-
免疫原
- Recombinant protein corresponding to Mouse BNC1/BNC
-
-
-
-
应用备注
- WB (H,M,R) 1:250-1:500
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
缓冲液
- PBS, pH 7.4, 0.02 % sodium azide
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- -20 °C
-
-
- Basonuclin 1 (BNC1)
-
别名
- BNC1/BNC
-
背景
- The zinc finger protein, basonuclin, is a putative rDNA transcription factor with highly restricted tissue distribution. Basonuclin is abundantly expressed in keratinocytes of the basal layer of the epidermis, the outer sheath of hair follicles and in the germ cells of the testis and ovary. In the epidermis, basonuclin, which is mainly localized to the cytoplasm, translocates to basal cell nuclei during different stages of keratinocyte growth. Basonuclin may enhance rRNA synthesis by elevating transcription from an rDNA promoter and inhibiting RNA polymerase I transcription through its zinc finger domain. Therefore, basonuclin may be a cell-type-specific transcription factor for rDNA transcription.
-
分子量
- 107 kDa
-
UniProt
- O35914
抗原
-