alpha Actinin 抗体
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北京 101111
Quick Overview for alpha Actinin 抗体 (ABIN7073023)
抗原
See all alpha Actinin (ACTN) 抗体适用
宿主
克隆类型
标记
应用范围
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交叉反应
- 小鼠, 大鼠
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纯化方法
- Affinity purification
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免疫原
- KLH conjugated Synthetic peptide corresponding to Human ACTN1
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应用备注
- WB (H,M,R) 1:500-1:1000, IHC/IF (M,R) 1:500-1:1000/1:500-1:1000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS, pH 7.4, 0.02 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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- alpha Actinin (ACTN) (alpha-Actinin Skeletal Muscle (ACTN))
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别名
- alpha Actinin
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背景
- Alpha actinins belong to the spectrin gene superfamily which represents a diverse group of cytoskeletal proteins, including the alpha and beta spectrins and dystrophins. Alpha actinin is an actin-binding protein with multiple roles in different cell types. In nonmuscle cells, the cytoskeletal isoform is found along microfilament bundles and adherens-type junctions, where it is involved in binding actin to the membrane. In contrast, skeletal, cardiac, and smooth muscle isoforms are localized to the Z-disc and analogous dense bodies, where they help anchor the myofibrillar actin filaments.
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分子量
- 103 kDa
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基因ID
- 109711
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NCBI登录号
- NP_001093
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UniProt
- P12814
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途径
- Cell-Cell Junction Organization, Negative Regulation of Transporter Activity
抗原
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