ACTH 抗体
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北京 101111
Quick Overview for ACTH 抗体 (ABIN7072981)
抗原
See all ACTH 抗体适用
宿主
克隆类型
标记
应用范围
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交叉反应
- 大鼠
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纯化方法
- Affinity purification
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免疫原
- KLH conjugated Synthetic peptide corresponding to Mouse ACTH
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应用备注
- WB (M,R) 1:500
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS, pH 7.4, 0.02 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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- ACTH (Adrenocorticotropic hormone (ACTH))
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别名
- ACTH
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背景
- Pro-opiomelanocortin (POMC) is a precursor polypeptide with 266 amino acid residues. POMC is synthesized in the pituitary from the 285-amino-acid-long polypeptide precursor pre-pro-opiomelanocortin (pre-POMC), by the removal of a 44-amino-acid-long signal peptide sequence during translation. POMC is cleaved to give rise to multiple peptide hormones(α-MSH, ACTH, β-Endorphin and [Met]enkephalin). Adrenocorticotropic hormone (ACTH, also adrenocorticotropin, corticotropin) is a polypeptide tropic hormone produced by and secreted by the anterior pituitary gland. It is also used as a medication and diagnostic agent.. ACTH is an important component of the hypothalamic-pituitary-adrenal axis and is often produced in response to biological stress. Its principal effects are increased production and release of cortisol by the cortex of the adrenal gland. ACTH is also related to the circadian rhythm in many organisms.
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分子量
- 30 kDa
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基因ID
- 18976
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NCBI登录号
- NP_001265510
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UniProt
- P01193
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途径
- Metabolism of Steroid Hormones and Vitamin D, Peptide Hormone Metabolism, Hormone Activity
抗原
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