ADRA1B 抗体
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北京 101111
Quick Overview for ADRA1B 抗体 (ABIN7072974)
抗原
See all ADRA1B 抗体适用
宿主
克隆类型
标记
应用范围
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交叉反应
- 人, 大鼠
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纯化方法
- Affinity purification
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免疫原
- KLH conjugated Synthetic peptide corresponding to Mouse ADRA1B
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应用备注
- IHC/IF (H,M,R) 1:400-1:1200
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限制
- 仅限研究用
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缓冲液
- , 0.02 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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- ADRA1B (Adrenergic, alpha-1B-, Receptor (ADRA1B))
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别名
- ADRA1B
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背景
- Alpha-1-adrenergic receptors (alpha-1-ARs) are members of the G protein-coupled receptor superfamily. They activate mitogenic responses and regulate growth and proliferation of many cells. There are 3 alpha-1-AR subtypes: alpha-1A, -1B and -1D, all of which signal through the Gq/11 family of G-proteins and different subtypes show different patterns of activation. This gene encodes alpha-1B-adrenergic receptor, which induces neoplastic transformation when transfected into NIH 3T3 fibroblasts and other cell lines. Thus, this normal cellular gene is identified as a protooncogene. This gene comprises 2 exons and a single large intron of at least 20 kb that interrupts the coding region.
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UniProt
- P97717
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途径
- AMPK Signaling, Carbohydrate Homeostasis, Regulation of Carbohydrate Metabolic Process
抗原
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