Recombinant SARS-CoV-2 Spike 抗体 (C-Term, Extracellular Domain, RBD)
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Quick Overview for Recombinant SARS-CoV-2 Spike 抗体 (C-Term, Extracellular Domain, RBD) (ABIN7072712)
抗原
See all SARS-CoV-2 Spike (SARS-CoV-2 S) 抗体抗体类型
适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- C-Term, Extracellular Domain, RBD
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原理
- Anti-Spike protein (RBD) [Sb#14], Mouse IgG1-Fc Fusion,
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特异性
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This antibody recognizes and binds the SARS CoV 2 C-terminal receptor binding domain (RBD) located in the extracellular portion of the spike protein.
Application Notes original Clone: This antibody is recommended for detection of SARS CoV 2 or 2019-nCoV. Its high specificity to the novel coronavirus SARS-Cov-2 was confirmed via ELISA testing (Walter et al., 2020). Furthermore, grating-coupled interferometry demonstrated that this antibody binds the receptor binding domain (RBD) of the spike protein with high affinity (Walter et al., 2020). Subsequent testing showed that this clone exhibits exceptionally strong inhibition of binding of SARS-Cov-2 RBD to hACE2, which is the receptor for the virus (signal of RBD association with hACE2 decreased over 90 % ) (Walter et al., 2020).
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产品特性
- This chimeric mouse antibody was made using the variable domain sequences of the original VHH format, for improved compatibility with existing reagents, assays and techniques.
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纯化方法
- Purified antibody.
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免疫原
- This clone was originally isolated in a form of a synthetic nanobody (sybody) via a 'target swap' selection procedure against RBD-vYFP using ribosomal display and against RBD-Fc fusion during phage display rounds.
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亚型
- IgG1-Fc Fusion
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anti-SARS-CoV-2 Spike (SARS-CoV-2 S) (C-Term) antibody
SARS-CoV-2 S 适用: SARS Coronavirus-2 (SARS-CoV-2), SARS Coronavirus (SARS-CoV) ELISA, WB, IF, IHC 宿主: 兔 Polyclonal unconjugated
anti-SARS-CoV-2 Spike (SARS-CoV-2 S) antibodySARS-CoV-2 S 适用: SARS Coronavirus-2 (SARS-CoV-2), SARS CoV-2 Alpha, SARS CoV-2 Beta, SARS CoV-2 Gamma ELISA, WB 宿主: 兔 Polyclonal unconjugated
anti-SARS-CoV-2 Spike (SARS-CoV-2 S) (AA 319-541) antibodyAnimal-Free SARS-CoV-2 S 适用: SARS Coronavirus-2 (SARS-CoV-2) ELISA, WB, FACS, IF 宿主: 小鼠 Monoclonal AB68-A09 unconjugated Recombinant Antibody
anti-SARS-CoV-2 Spike (SARS-CoV-2 S) (AA 319-541), (Receptor Binding Domain) antibody (Fc Tag)SARS-CoV-2 S 适用: SARS Coronavirus-2 (SARS-CoV-2) ELISA, Neut, GICA 宿主: Human Monoclonal A1 Fc Tag single-domain Antibody (sdAb) Recombinant Antibody
anti-SARS-CoV-2 Spike (SARS-CoV-2 S) antibodySARS-CoV-2 S 适用: SARS Coronavirus-2 (SARS-CoV-2) ELISA 宿主: Human Monoclonal AM015553 (553-15) unconjugated Recombinant Antibody
anti-SARS-CoV-2 Spike (SARS-CoV-2 S) antibodySARS-CoV-2 S 适用: SARS Coronavirus-2 (SARS-CoV-2) ELISA, WB 宿主: Human Monoclonal AM004414 (414-4) unconjugated Recombinant Antibody
anti-SARS-CoV-2 Spike (SARS-CoV-2 S) (AA 16-685) antibody (Fc Tag,HRP)SARS-CoV-2 S 适用: SARS Coronavirus-2 (SARS-CoV-2) ELISA 宿主: 小鼠 Monoclonal H6 Fc Tag,HRP scFv fragment Recombinant Antibody
anti-SARS-CoV-2 Spike (SARS-CoV-2 S) (AA 16-685) antibodySARS-CoV-2 S 适用: SARS Coronavirus-2 (SARS-CoV-2) ELISA, GICA 宿主: Chimeric Chimeric H6 unconjugated Recombinant Antibody
anti-SARS-CoV-2 Spike (SARS-CoV-2 S) (AA 319-541), (RBD) antibodySARS-CoV-2 S 适用: SARS Coronavirus-2 (SARS-CoV-2) ELISA, FACS 宿主: 兔 Monoclonal DM54 unconjugated
anti-SARS-CoV-2 Spike (SARS-CoV-2 S) (RBD) antibodyVerified SARS-CoV-2 S 适用: SARS Coronavirus-2 (SARS-CoV-2) ELISA, WB 宿主: 山羊 Polyclonal unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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说明
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OriginalSpeciesName: Dromedary
OriginalFormat: VHH
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限制
- 仅限研究用
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缓冲液
- PBS with 0.02 % Proclin 300.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.
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- SARS-CoV-2 Spike (SARS-CoV-2 S)
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别名
- SARS-CoV2 Spike protein
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物质类
- Viral Protein
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背景
- Receptor Binding Domain, SARS CoV 2 S glycoprotein, Sb45, COVID-19 Spike protein, RBD, Receptor Binding Domain, E2 glycoprotein, E2, Human coronavirus 2 spike glycoprotein, Peplomer protein, S glycoprotein, SARS coronavirus 2 S protein, SARS coronavirus 2 Spike Protein, SARS CoV 2 Spike protein, SARS CoV 2, SARS-CoV-2 S protein, SARSCoV2, SARS-COV-2 S protein, SARS-COV-2 Spike glycoprotein, SARSCOV2 Spike protein, Severe acute respiratory syndrome 2 spike glycoprotein, Severe acute respiratory syndrome virus 2 spike glycoprotein, Spike glycoprotein, 2019-nCoV, SARS-CoV2
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UniProt
- P0DTC2
抗原
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