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Recombinant beta 2 Adrenergic Receptor 抗体

This anti-beta 2 Adrenergic Receptor antibody is a 兔 Chimeric antibody detecting beta 2 Adrenergic Receptor in WB, ELISA, IF 和 IP. Suitable for 人.
产品编号 ABIN7072671
发货至: 中国

Quick Overview for Recombinant beta 2 Adrenergic Receptor 抗体 (ABIN7072671)

抗原

See all beta 2 Adrenergic Receptor (ADRB2) 抗体
beta 2 Adrenergic Receptor (ADRB2) (Adrenergic, beta-2-, Receptor, Surface (ADRB2))

抗体类型

Recombinant Antibody

适用

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克隆类型

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Chimeric

标记

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This beta 2 Adrenergic Receptor antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunoprecipitation (IP)

克隆位点

13D6
  • 原理

    Anti-Beta 2 adrenergic receptor [13D6], Rabbit IgG, kappa

    特异性

    13D6 antibody recognizes human beta-2 adrenergic receptor. It was reported that this antibody recognizes extracellualr domains of the receptor (Han et al., 2012). Beta-adrenergic receptors mediate the catecholamine-induced activation of adenylate cyclase through the action of G proteins. The beta-2-adrenergic receptor binds adrenaline with far grater affinity than noradrenaline.

    产品特性

    Original Species of Ab: Mouse

    Original Format of Ab: IgG1

    纯化方法

    Protein A affinity purified

    免疫原

    This antibody was raised by immunizing mice with beta-2 adrenergic receptor.

    亚型

    IgG kappa
  • 应用备注

    This antibody is recommended for the identification and analysis of the β2-adrenergic receptor. For instance, tt was used to immunostain vascular smooth muscle cells (VSMCs) against beta-2-adrenergic receptor to determine the fate of beta-2ARs ubiquitinated in a carvedilol responsive manner (Han et al., 2012). Furthermore, the antibody was utilized in the quantification of the surface level of β-2ARs via ELISA (Han et al., 2012).

    说明

    This chimeric rabbit antibody was made using the variable domain sequences of the original Mouse IgG1 format, for improved compatibility with existing reagents, assays and techniques.

    限制

    仅限研究用
  • 浓度

    1 mg/mL

    缓冲液

    PBS with 0.02 % Proclin 300.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.
  • 抗原

    beta 2 Adrenergic Receptor (ADRB2) (Adrenergic, beta-2-, Receptor, Surface (ADRB2))

    别名

    Beta 2 adrenergic receptor

    背景

    R11E1, Beta-2 adrenergic receptor, Beta-2 adrenoreceptor, Beta-2 adrenoceptor, β-2 adrenergic receptor, β-2 adrenoreceptor, β-2 adrenoceptor, β2AR, β2-AR, I3D6

    UniProt

    P07550

    途径

    cAMP Metabolic Process, Synaptic Membrane, Regulation of G-Protein Coupled Receptor Protein Signaling, Brown Fat Cell Differentiation
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