Recombinant B7-H6 抗体 (Extracellular Domain)
Quick Overview for Recombinant B7-H6 抗体 (Extracellular Domain) (ABIN7072649)
抗原
See all B7-H6 (NCR3LG1) 抗体抗体类型
适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
 - Extracellular Domain
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原理
 - Anti-B7-H6 [17B1.3], Rabbit IgG, kappa
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特异性
 - MAb 17B1.3 specifically recognises B7-H6. 17B1.3 reacted with human tumour cell lines constitutively expressing B7-H6 such as HeLa cells. Fab 17B1.3 does not interfere with the binding of B7-H6 to NKp30, but nevertheless blocks NK cell activation.
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产品特性
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Original Species of Ab: Mouse
Original Format of Ab: IgG1
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纯化方法
 - Protein A affinity purified
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免疫原
 - Immunised mice with extracellular domain of human B7-H6 and selected on the basis of specific reactivity by P815.B7-H6, but not with P815.B7-H1.
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亚型
 - IgG kappa
 
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应用备注
 - B7-H6 is not detected in normal human tissues at steady state but is expressed on tumour cells, so tumour cells can be detected by NK cells. This article describes the study of the mechanisms that govern the induction of B7-H6 on primary cells as well as its consequences in vitro and in vivo.
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说明
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This chimeric rabbit antibody was made using the variable domain sequences of the original Mouse IgG1 format, for improved compatibility with existing reagents, assays and techniques.
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限制
 - 仅限研究用
 
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浓度
 - 1 mg/mL
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缓冲液
 - PBS with 0.02 % Proclin 300.
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储存液
 - ProClin
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注意事项
 - This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
 - 4 °C,-20 °C
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储存方法
 - Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.
 
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- B7-H6 (NCR3LG1) (Natural Killer Cell Cytotoxicity Receptor 3 Ligand 1 (NCR3LG1))
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别名
 - B7-H6
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背景
 - B7H6, B7 homolog 6, Natural cytotoxicity triggering receptor 3 ligand 1, NCR3LG1, DKFZp686O2416
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UniProt
 - Q68D85
 
抗原
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