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Recombinant VCAM1 抗体

This anti-VCAM1 antibody is a 兔 Chimeric antibody detecting VCAM1 in FACS 和 BP. Suitable for 人.
产品编号 ABIN7072646
发货至: 中国

Quick Overview for Recombinant VCAM1 抗体 (ABIN7072646)

抗原

See all VCAM1 抗体
VCAM1 (Vascular Cell Adhesion Molecule 1 (VCAM1))

抗体类型

Recombinant Antibody

适用

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克隆类型

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Chimeric

标记

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This VCAM1 antibody is un-conjugated

应用范围

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Flow Cytometry (FACS), Blocking Peptide (BP)

克隆位点

B-K9 (C106-K9)
  • 原理

    Anti-CD106 [B-K9 (C106-K9)], Rabbit IgG, kappa

    特异性

    B-K9 antibody recognizes CD106 (VCAM1). CD106 is a member of the Ig superfamily. It is a cell surface sialoglycoprotein expressed by cytokine-activated endothelium. This type I membrane protein mediates leukocyte-endothelial cell adhesion and signal transduction, and may play a role in the development of artherosclerosis and rheumatoid arthritis.

    产品特性

    Original Species of Ab: Mouse

    Original Format of Ab: IgG1

    纯化方法

    Protein A affinity purified

    免疫原

    This antibody was raised by immunizing Balb/c mice against activated human umbilical vein endothelial cells (HUVEC).

    亚型

    IgG kappa
  • 应用备注

    B-K9 antibody inhibits the binding of leukocytes to VCAM-1 on stimulated endothelial cells, and thus it blocks the ability of white blood cells to attach themselves to the activated epithelium during, for instance, inflammation. Consequently, this antibody might be used in research where leukocytes adhesion-blocking is required (Uotila et al., 2014, Wagner et al. 2011).

    说明

    This chimeric rabbit antibody was made using the variable domain sequences of the original Mouse IgG1 format, for improved compatibility with existing reagents, assays and techniques.

    限制

    仅限研究用
  • 浓度

    1 mg/mL

    缓冲液

    PBS with 0.02 % Proclin 300.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.
  • 抗原

    VCAM1 (Vascular Cell Adhesion Molecule 1 (VCAM1))

    别名

    CD106

    背景

    VCAM1, Vascular cell adhesion protein 1, V-CAM 1, INCAM-100

    UniProt

    P19320

    途径

    Carbohydrate Homeostasis
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