Recombinant CD43 抗体
-
- 抗原 See all CD43 (SPN) 抗体
- CD43 (SPN) (Sialophorin (SPN))
- 抗体类型
- Recombinant Antibody
-
适用
- 人
-
宿主
- 兔
-
克隆类型
- Chimeric
-
标记
- This CD43 antibody is un-conjugated
-
应用范围
- Flow Cytometry (FACS), Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunoprecipitation (IP)
- 原理
- Anti-CD43 [84-3C1], Rabbit IgG, kappa
- 特异性
- This antibody recognizes CD43 which is a predominant cell surface sialoprotein of leukocytes which regulates multiple T-cell functions, including T-cell activation, proliferation, differentiation, trafficking and migration.
- 产品特性
-
Original Species of Ab: Mouse
Original Format of Ab: IgG2b
- 纯化方法
- Protein A affinity purified
- 免疫原
- This antibody was raised by immunizng mice with stimulated human leukocytes.
- 克隆位点
- 84-3C1
- 亚型
- IgG kappa
- Top Product
- Discover our top product SPN Primary Antibody
-
anti-Sialophorin (SPN) antibody
SPN 适用: 人 FACS, WB, IHC, IF, StM 宿主: 小鼠 Monoclonal DF-T1 unconjugated
anti-Sialophorin (SPN) antibodySPN 适用: 人 FACS, WB, IHC (p), IP, Func 宿主: 小鼠 Monoclonal MEM-59 unconjugated
anti-Sialophorin (SPN) (AA 276-400) antibodySPN 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Sialophorin (SPN) antibodySPN 适用: 人 FACS, WB, IHC, IF, StM 宿主: 小鼠 Monoclonal rSPN-839 unconjugated Recombinant Antibody
anti-Sialophorin (SPN) antibodySPN 适用: 人 FACS, WB, IHC, IF, StM 宿主: 兔 Monoclonal SPN-1766R unconjugated Recombinant Antibody
anti-Sialophorin (SPN) antibodySPN 适用: 人, 小鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Sialophorin (SPN) (AA 1-400) antibodySPN 适用: 人 FACS, WB 宿主: 小鼠 Polyclonal unconjugated
anti-Sialophorin (SPN) (AA 20-253) antibodySPN 适用: 人 FACS, ELISA 宿主: 小鼠 Monoclonal 1H8B10 unconjugated
anti-Sialophorin (SPN) (AA 272-400) antibodySPN 适用: 人, 小鼠, 大鼠 FACS, WB, IHC, IF, IHC (fro), ICC 宿主: 兔 Polyclonal unconjugated
anti-Sialophorin (SPN) (AA 1-400) antibodySPN 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 3G8 unconjugated
-
- 应用备注
- This antibody can be used in the identification of malignant lymphomas. CD43 is expressed on 22-37 % of B-cell lymphomas and, at the same time, it is not expressed on reactive B-cells. Consequently, B-lineage population that co-expresses CD43 is highly likely to be a malignant lymphoma. If used with an anti-CD20 antibody, this clone may be utilized in the immunophenotyping of the lymphomas in formalin-fixed tissues, as Co-staining of a lymphoid infiltrate with anti-CD20 and anti-CD43 usually indicates lymphoma. Importantly, 84-3C1 antibody can be used for the detection of CD43 via various methods. For instance, it was successful in indetifying that antigen in a lysate of dendritic cells' platellet via Western blot (Julien et al., 2007). Finally, another group used this antibody during flow cytometric analysis a sample of B-cells (Yoon et al., 2017).
- 说明
-
This chimeric rabbit antibody was made using the variable domain sequences of the original Mouse IgG2b format, for improved compatibility with existing reagents, assays and techniques.
- 限制
- 仅限研究用
-
- 浓度
- 1 mg/mL
- 缓冲液
- PBS with 0.02 % Proclin 300.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.
-
- 抗原
- CD43 (SPN) (Sialophorin (SPN))
- 别名
- CD43 (SPN 产品)
- 背景
- Leukosialin, Sialophorin, GPL115, Galactoglycoprotein, GALGP, Leukocyte sialoglycoprotein
- UniProt
- P16150
- 途径
- Regulation of Leukocyte Mediated Immunity
-
