Recombinant IL-10RA 抗体 (Extracellular Domain)
Quick Overview for Recombinant IL-10RA 抗体 (Extracellular Domain) (ABIN7072606)
抗原
See all IL-10RA (IL10RA) 抗体抗体类型
适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- Extracellular Domain
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原理
- Anti-IL-10R [1B1.3a], Rabbit IgG, kappa
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特异性
- This antibody recognises mouse IL-10R which is a cell surface glycoprotein and a receprot for anti-inflammatory IL-10. The epitope recognised by this antibody has been localised to the ligand binding domain within the extracellular region of mouse IL-10R.
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产品特性
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Original Species of Ab: Rat
Original Format of Ab: IgG1
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纯化方法
- Protein A affinity purified
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免疫原
- This antibody was raised by immunising rats with the purified recombinant extracellular region of mouse Interleukin 10 Receptor.
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亚型
- IgG kappa
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anti-Interleukin 10 Receptor, alpha (IL10RA) (AA 132-235) antibody
IL10RA 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 10 Receptor, alpha (IL10RA) (Ser560) antibodyIL10RA 适用: 人 WB, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 10 Receptor, alpha (IL10RA) (C-Term) antibodyIL10RA 适用: 人 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 10 Receptor, alpha (IL10RA) (pTyr496) antibodyIL10RA 适用: 人 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 10 Receptor, alpha (IL10RA) (AA 128-177) antibodyIL10RA 适用: 人, Cow, Pig, 马, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 10 Receptor, alpha (IL10RA) antibodyIL10RA 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 10 Receptor, alpha (IL10RA) (AA 147-175) antibodyIL10RA 适用: 人 WB, FACS, IF 宿主: 兔 Polyclonal RB23343 unconjugated
anti-Interleukin 10 Receptor, alpha (IL10RA) (AA 81-180) antibodyIL10RA 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 10 Receptor, alpha (IL10RA) (AA 132-235) antibodyIL10RA 适用: 人 WB 宿主: 小鼠 Monoclonal C9 unconjugated
anti-Interleukin 10 Receptor, alpha (IL10RA) antibodyIL10RA 适用: 小鼠 FACS, IF, Neut 宿主: 大鼠 Monoclonal 1B1-3a unconjugated
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应用备注
- 1B1.3a has been widely applied in flow cytometric analyses where the detection of IL-10R was needed. Furthermore, this antibody was also successfully utilised as a blocking agent, one group used it to demonstrate that IL-10 mediates suppressive activity, by targeting its receptor IL-10R with this antibody (Wang et al., 2004). Castro et al. (2000) demonstrated that 1B1.3a is able to make a soluble peptide or protein antigen immunogenic for subsequent Th1 recall responses in a situation when there is an additional signal, such as LPS, activating the immune system. Consequently, this antibody is a hugely promising agent in the potential development of vaccines for immunotherapy. Similarly, Vicari and colleagues (2002) showed that this antibody has an enormous potential as a therapeutic anti-tumour agent when combined with the administration of CpG to stimulate the immune system.
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说明
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This chimeric rabbit antibody was made using the variable domain sequences of the original Rat IgG1 format, for improved compatibility with existing reagents, assays and techniques.
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限制
- 仅限研究用
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浓度
- 1 mg/mL
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缓冲液
- PBS with 0.02 % Proclin 300.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.
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- IL-10RA (IL10RA) (Interleukin 10 Receptor, alpha (IL10RA))
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别名
- IL-10R
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背景
- CD210, Interleukin-10 receptor subunit, Interleukin-10 receptor subunit alpha, Il10ra Il10r, IL-10 receptor subunit alpha, IL-10R subunit alpha, IL-10RA, CDw210a, Interleukin-10 receptor subunit 1, IL-10R subunit 1, IL-10R1, IBI-3A, 1B1-3A
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UniProt
- Q61727
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途径
- Growth Factor Binding
抗原
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