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Recombinant CD96 抗体

This anti-CD96 antibody is a 兔 Chimeric antibody detecting CD96 in FACS 和 BP. Suitable for 小鼠.
产品编号 ABIN7072565
发货至: 中国

Quick Overview for Recombinant CD96 抗体 (ABIN7072565)

抗原

See all CD96 抗体
CD96

抗体类型

Recombinant Antibody

适用

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  • 6
  • 1
  • 1
小鼠

宿主

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  • 9
  • 2
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  • 1
  • 1

克隆类型

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Chimeric

标记

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This CD96 antibody is un-conjugated

应用范围

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  • 10
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Flow Cytometry (FACS), Blocking Peptide (BP)

克隆位点

6A6
  • 原理

    Anti-CD96 [6A6], Rabbit IgG, lambda

    特异性

    This antibody is specific for murine CD96, and recognises an epitope in the first Ig domain.

    产品特性

    Original Species of Ab: Rat

    Original Format of Ab: IgG2a

    纯化方法

    Protein A affinity purified

    免疫原

    This antibody was raised by immunising rats with murine CD96.

    亚型

    IgG lambda
  • 应用备注

    This antibody blocks murine CD96-CD155 interaction, and has been shown to bind to the first Ig domain of CD96 and compete with CD155 binding (Roman Aguilera et al, 2018). This antibody displays significant anti-metastatic activity in four experimental lung metastases models and one spontaneous tumour metastasis model (Roman Aguilera et al, 2018), with a potency greater than the anti-CD96 monoclonal antibodies 3.3 and 8B10. The binding specificity of this antibody has been determined in flow cytometric analysis of HEK-293 cells transfected with a range of CD96 Ig domain chimeric constructs (Roman Aguilera et al, 2018).

    说明

    This chimeric rabbit antibody was made using the variable domain sequences of the original rat IgG2a format, for improved compatibility with existing reagents, assays and techniques.

    限制

    仅限研究用
  • 浓度

    1 mg/mL

    缓冲液

    PBS with 0.02 % Proclin 300.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.
  • 抗原

    CD96

    别名

    CD96

    背景

    TACTILE, T-cell surface protein tactile, T cell-activated increased late expression protein

    UniProt

    Q3U0X8
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