Recombinant IL-9 抗体
Quick Overview for Recombinant IL-9 抗体 (ABIN7072551)
抗原
See all IL-9 (IL9) 抗体抗体类型
适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- Anti-IL-9 [D9302C12], Rabbit IgG, kappa
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特异性
- This antibody is specific for murine IL-9.
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产品特性
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Original Species of Ab: Hamster, Armenian
Original Format of Ab: IgG
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纯化方法
- Protein A affinity purified
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免疫原
- This antibody was raised by immunising Armenian hamsters with Baculovirus-expressed, recombinant murine IL-9.
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亚型
- IgG kappa
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应用备注
- In vitro, this antibody has inhibitory effects on IL-9 bioactivity, and inhibits the differentiation of Th17 cells and consequent production of IL-17 (Li et al, 2010). This antibody is also able to neutralise IL-9 in vivo (Li et al, 2010). Administration of this antibody suppresses acute experimental autoimmune encephalomyelitis (EAE), with an observed reduction in MOG-specific Th1 and Th17 cells in the periphery and the CNS (Li et al, 2010).
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说明
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This chimeric rabbit antibody was made using the variable domain sequences of the original Hamster IgG2 format, for improved compatibility with existing reagents, assays and techniques.
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限制
- 仅限研究用
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浓度
- 1 mg/mL
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缓冲液
- PBS with 0.02 % Proclin 300.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.
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- IL-9 (IL9) (Interleukin 9 (IL9))
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别名
- IL-9
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背景
- Interleukin-9, IL9, Cytokine P40, T-cell growth factor P40
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UniProt
- P15247
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途径
- JAK/STAT Signaling
抗原
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