Recombinant ITGAL 抗体
Quick Overview for Recombinant ITGAL 抗体 (ABIN7072545)
抗原
See all ITGAL 抗体抗体类型
适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- Anti-CD11a [MHM24], Rabbit IgG, kappa
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特异性
- MHM24 binds to the CD11a subunit of lymphocyte function-associated antigen. It binds to both the high- and low-affinity forms of the antigen.
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产品特性
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Original Species of Ab: Mouse
Original Format of Ab: IgG
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纯化方法
- Protein A affinity purified
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免疫原
- Spleen cells from BALB/c mice immunised with EBV-transformed human lymphoblastoid cells were fused with P3-NSUlAg4.1 myeloma cells and the resulting hybridomas were screened for antibody production by a radioimmunoassay on T and B cell lines.
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亚型
- IgG kappa
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anti-Integrin alpha-L (ITGAL) (AA 26-306) antibody
ITGAL 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Integrin alpha-L (ITGAL) (AA 26-194) antibodyITGAL 适用: 人 FACS, WB, IHC, ELISA 宿主: 小鼠 Monoclonal 5G7C5 unconjugated
anti-Integrin alpha-L (ITGAL) antibodyITGAL 适用: 人, 小鼠, 大鼠 IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Integrin alpha-L (ITGAL) antibodyITGAL 适用: 人 FACS, IP, IHC 宿主: 小鼠 Monoclonal 38 unconjugated
anti-Integrin alpha-L (ITGAL) (AA 201-500) antibodyITGAL 适用: 人 WB, IHC, IF, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Integrin alpha-L (ITGAL) antibodyITGAL 适用: 小鼠 FACS, IP, IHC (fro) 宿主: 大鼠 Monoclonal M17-4 unconjugated
anti-Integrin alpha-L (ITGAL) antibodyITGAL 适用: 人 FACS, IP, Func 宿主: 小鼠 Monoclonal MEM-25 unconjugated
anti-Integrin alpha-L (ITGAL) antibodyITGAL 适用: 人 FACS, IP 宿主: 小鼠 Monoclonal MEM-25 unconjugated
anti-Integrin alpha-L (ITGAL) antibody (Biotin)ITGAL 适用: 人 FACS, IP 宿主: 小鼠 Monoclonal MEM-25 Biotin
anti-Integrin alpha-L (ITGAL) antibody (PE)ITGAL 适用: 人 FACS 宿主: 小鼠 Monoclonal MEM-25 PE
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应用备注
- Cytofluorography was used to show the binding of MHM24 to peripheral blood lymphocytes, with 97.3 % of cells stained by MHM24 (Hildreth et al, 1983). In inhibition experiments, MHM24 inhibited T cell-mediated lysis of virus-infected cells (Hildreth et al, 1983). Additionally, MHM24 inhibited NK cell-mediated lysis (Hildreth et al, 1983).Flow cytometry showed MHM24 exhibits non-selective binding to high-affinity and low-affinity forms of LFA-1 (Huang et al, 2006). Murine MHM24 was humanised and shown to prevent adhesion of human T cells to human keratinocytes and the proliferation of T cells in response to nonautologous leukocytes (Werther et al, 1996).
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说明
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This chimeric rabbit antibody was made using the variable domain sequences of the original Mouse IgG format, for improved compatibility with existing reagents, assays and techniques.
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限制
- 仅限研究用
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浓度
- 1 mg/mL
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缓冲液
- PBS with 0.02 % Proclin 300.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.
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- ITGAL (Integrin alpha-L (ITGAL))
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别名
- CD11a
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背景
- Integrin alpha-L, CD11 antigen-like family member A, leukocyte function-associated molecule 1 alpha chain, human lymphocyte function antigen
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UniProt
- P20701
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途径
- Activated T Cell Proliferation, Integrin Complex
抗原
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