Recombinant Transferrin Receptor 抗体
Quick Overview for Recombinant Transferrin Receptor 抗体 (ABIN7072542)
抗原
See all Transferrin Receptor (TFRC) 抗体抗体类型
适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- Anti-Transferrin receptor [R17 217.1.3], Rabbit IgG, kappa
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特异性
- The transferrin receptor is necessary for cellular iron uptake by the process of receptor-mediated endocytosis. Mice that are deficient in this receptor show impaired erythroid development and abnormal iron homeostasis.
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产品特性
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Original Species of Ab: Rat
Original Format of Ab: IgG2a
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纯化方法
- Protein A affinity purified
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免疫原
- The antibody was obtained from a fusion of the murine myeloma S 194/5.XXO.BU. 1 with spleen cells from a BDIX rat immunized with the Friend erythroleukemia 745.6.
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亚型
- IgG kappa
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应用备注
- R17 217.1.3 was used in conjunction with flow cytometry to identify murine hematopoietic progenitor cells expressing the transferrin receptor (Lesley et al, 1984). Injection of mice with R17 217.1.3 results in CD71+ erythroid splenocyte cell depletion (Torow et al, 2015).
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说明
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This chimeric rabbit antibody was made using the variable domain sequences of the original Rat IgG2a format, for improved compatibility with existing reagents, assays and techniques.
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限制
- 仅限研究用
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浓度
- 1 mg/mL
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缓冲液
- PBS with 0.02 % Proclin 300.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.
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- Transferrin Receptor (TFRC) (Transferrin Receptor (p90, CD71) (TFRC))
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别名
- Transferrin receptor
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背景
- CD71, Transferrin receptor protein 1, TR, , TfR1, Trfr
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途径
- Transition Metal Ion Homeostasis
抗原
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