Recombinant Fc epsilon RI/FCER1A 抗体
Quick Overview for Recombinant Fc epsilon RI/FCER1A 抗体 (ABIN7072532)
抗原
See all Fc epsilon RI/FCER1A (FCER1A) 抗体抗体类型
适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- Anti-FceR1 alpha [Mar-1], Rabbit IgG, lambda
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特异性
- This antibody specifically targets the non-signalling alpha chain of the FceR1 complex.
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产品特性
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Original Species of Ab: Hamster, Armenian
Original Format of Ab: IgG
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纯化方法
- Protein A affinity purified
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亚型
- IgG lambda
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anti-Fc Fragment of IgE Receptor Ia (FCER1A) (AA 1-257) antibody
FCER1A 适用: 人 WB, ELISA, RNAi 宿主: 小鼠 Monoclonal 2C12-3B6 unconjugated
anti-Fc Fragment of IgE Receptor Ia (FCER1A) (AA 42-103) antibodyFCER1A 适用: 人, 小鼠 FACS, WB, ELISA 宿主: 小鼠 Monoclonal 1F2A9 unconjugated
anti-Fc Fragment of IgE Receptor Ia (FCER1A) (AA 26-205) antibodyFCER1A 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Fc Fragment of IgE Receptor Ia (FCER1A) antibodyFCER1A 适用: 人 FACS, WB, ELISA, IP, IF 宿主: 小鼠 Monoclonal 9E1 unconjugated
anti-Fc Fragment of IgE Receptor Ia (FCER1A) (AA 1-257) antibodyFCER1A 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Fc Fragment of IgE Receptor Ia (FCER1A) (C-Term) antibodyFCER1A 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Fc Fragment of IgE Receptor Ia (FCER1A) (AA 101-220) antibodyFCER1A 适用: 人 WB, ELISA, ICC, IHC (p), IHC (fro), IF (cc), IF (p) 宿主: 兔 Polyclonal unconjugated
anti-Fc Fragment of IgE Receptor Ia (FCER1A) (AA 24-204) antibodyFCER1A 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Fc Fragment of IgE Receptor Ia (FCER1A) antibody (APC)FCER1A 适用: 小鼠 FACS 宿主: Armenian Hamster Monoclonal MAR-1 APC
anti-Fc Fragment of IgE Receptor Ia (FCER1A) (AA 1-257) antibodyFCER1A 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
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应用备注
- This antibody has been used in flow cytometric analysis of FceR1 alpha cell surface expression by basophils (Min et al, 2004, Chen et al, 2009), and immunohistochemical analysis of epidermal sheets (Holzmann et al, 2004). It has also been used in immunoprecipitation analysis of cell lysates from lung cDCs and MC/9 mast cells (Grayson et al, 2007). In vitro incubation of basophils with this antibody blocks subsequent MAR-1 staining, but does not activate basophil IL-4 production (Sokol et al, 2008). Intravenous treatment of mice with this antibody results in basophil depletion in peripheral blood, spleen, bone marrow and liver, but not skin or intraperitoneal mast cell depletion (Sokol et al, 2008). Following treatment with this antibody, basophil-depleted mice display impaired Th2 differentiation upon papain immunisation (Sokol et al, 2008). However, MAR-1 treated mice respond normally to high-dose intravenous Ig in both the K/BxN serum transfer arthritis and collagen-induced arthritis models, despite basophil depletion (Campbell et al, 2014).
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说明
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This chimeric rabbit antibody was made using the variable domain sequences of the original Armenian Hamster IgG format, for improved compatibility with existing reagents, assays and techniques.
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限制
- 仅限研究用
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浓度
- 1 mg/mL
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缓冲液
- PBS with 0.02 % Proclin 300.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.
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- Fc epsilon RI/FCER1A (FCER1A) (Fc Fragment of IgE Receptor Ia (FCER1A))
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别名
- FceR1 alpha
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背景
- Fcer1a, Fc epsilon RI alpha, FceRIa, FceRI alpha, FceRI-α, high affinity IgE receptor, High affinity immunoglobulin epsilon receptor subunit alpha,Fce1a, Fc-epsilon RI-alpha, FcERI, IgE Fc receptor subunit alpha
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UniProt
- P20489
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途径
- Fc-epsilon Receptor Signaling Pathway, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process
抗原
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