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Recombinant IL-5 抗体

This anti-IL-5 antibody is a 兔 Chimeric antibody detecting IL-5 in ELISA 和 Neut. Suitable for 人.
产品编号 ABIN7072522
发货至: 中国

Quick Overview for Recombinant IL-5 抗体 (ABIN7072522)

抗原

See all IL-5 (IL5) 抗体
IL-5 (IL5) (Interleukin 5 (IL5))

抗体类型

Recombinant Antibody

适用

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宿主

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克隆类型

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Chimeric

标记

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This IL-5 antibody is un-conjugated

应用范围

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ELISA, Neutralization (Neut)

克隆位点

2E3
  • 原理

    Anti-IL-5 [2E3], Rabbit IgG, kappa

    特异性

    This antibody is specific for human rIL-5, and does not cross-react with human rIL-1α, rIL-lβ, rIL-4, rIL-8, rM-CSF, or rTGF-α.

    产品特性

    Original Species of Ab: Mouse

    Original Format of Ab: IgG2a

    纯化方法

    Protein A affinity purified

    免疫原

    This antibody was raised by immunising CAF1 mice with human recombinant IL-5.

    亚型

    IgG kappa
  • 应用备注

    This antibody has been show to inhibit the binding of human rIL-5 to the alpha chain of the IL-5 receptor (Ames et al, 1995). This antibody inhibits the proliferation of murine B13 cells in response to human IL-5 (Ames et al, 1995).Neutralising antibodies against IL-5 represent a potential therapeutic strategy for the treatment of eosinophilia. The specificity of this antibody for human IL-5 has been confirmed in ELISA analysis (Ames et al, 1995).

    说明

    This chimeric rabbit antibody was made using the variable domain sequences of the original Mouse IgG2a format, for improved compatibility with existing reagents, assays and techniques.

    限制

    仅限研究用
  • 浓度

    1 mg/mL

    缓冲液

    PBS with 0.02 % Proclin 300.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.
  • 抗原

    IL-5 (IL5) (Interleukin 5 (IL5))

    别名

    IL-5

    背景

    Interleukin 5, IL5, IL 5, Eosinophil differentiation factor

    UniProt

    C9JQP9

    途径

    JAK/STAT Signaling, Positive Regulation of Peptide Hormone Secretion, Production of Molecular Mediator of Immune Response, Feeding Behaviour
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