Recombinant IL-5 抗体
Quick Overview for Recombinant IL-5 抗体 (ABIN7072522)
抗原
See all IL-5 (IL5) 抗体抗体类型
适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- Anti-IL-5 [2E3], Rabbit IgG, kappa
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特异性
- This antibody is specific for human rIL-5, and does not cross-react with human rIL-1α, rIL-lβ, rIL-4, rIL-8, rM-CSF, or rTGF-α.
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产品特性
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Original Species of Ab: Mouse
Original Format of Ab: IgG2a
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纯化方法
- Protein A affinity purified
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免疫原
- This antibody was raised by immunising CAF1 mice with human recombinant IL-5.
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亚型
- IgG kappa
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应用备注
- This antibody has been show to inhibit the binding of human rIL-5 to the alpha chain of the IL-5 receptor (Ames et al, 1995). This antibody inhibits the proliferation of murine B13 cells in response to human IL-5 (Ames et al, 1995).Neutralising antibodies against IL-5 represent a potential therapeutic strategy for the treatment of eosinophilia. The specificity of this antibody for human IL-5 has been confirmed in ELISA analysis (Ames et al, 1995).
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说明
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This chimeric rabbit antibody was made using the variable domain sequences of the original Mouse IgG2a format, for improved compatibility with existing reagents, assays and techniques.
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限制
- 仅限研究用
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浓度
- 1 mg/mL
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缓冲液
- PBS with 0.02 % Proclin 300.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.
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- IL-5 (IL5) (Interleukin 5 (IL5))
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别名
- IL-5
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背景
- Interleukin 5, IL5, IL 5, Eosinophil differentiation factor
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UniProt
- C9JQP9
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途径
- JAK/STAT Signaling, Positive Regulation of Peptide Hormone Secretion, Production of Molecular Mediator of Immune Response, Feeding Behaviour
抗原
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