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Recombinant PDCD1LG2 抗体

This 兔 Chimeric antibody specifically detects PDCD1LG2 in WB, FACS, IP 和 BR. It exhibits reactivity toward 小鼠.
产品编号 ABIN7072432
发货至: 中国
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Quick Overview for Recombinant PDCD1LG2 抗体 (ABIN7072432)

抗原

See all PDCD1LG2 抗体
PDCD1LG2 (Programmed Cell Death 1 Ligand 2 (PDCD1LG2))

抗体类型

Recombinant Antibody

适用

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小鼠

宿主

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克隆类型

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Chimeric

标记

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This PDCD1LG2 antibody is un-conjugated

应用范围

  • 65
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Western Blotting (WB), Flow Cytometry (FACS), Immunoprecipitation (IP), Blocking Reagent (BR)

克隆位点

TY25
  • 原理

    Anti-PD-L2 [TY25], Rabbit IgG, kappa

    特异性

    This antibody binds to mouse PD-L2 and competes with PD-1 binding. It does not cross-react with PD-L1.

    产品特性

    Original Species of Ab: Rat

    Original Format of Ab: IgG2a

    纯化方法

    Protein A affinity purified

    免疫原

    This antibody was raised by immunising SD rats with B7-DC-transfected RAW264.7 cells and selected on B7-DC-transfected NRK.

    亚型

    IgG kappa
  • 应用备注

    This antibody has been used to detect murine PD-L2 by flow cytometry on stimulated dendritic cells as well as various mouse tumour cells. It also detects immunoprecipitates mouse PD-L2 and can be used to detect it by non-reducing Western Blot. TY25 inhibits PD-L2 binding to PD-1 transfected cells (Ansari et al. 2003, PMID: 12847137) and thereby blocks PD-L2 : PD-1 signalling.

    说明

    This chimeric rabbit antibody was made using the variable domain sequences of the original Rat IgG2a format, for improved compatibility with existing reagents, assays and techniques.

    限制

    仅限研究用
  • 浓度

    1 mg/mL

    缓冲液

    PBS with 0.02 % Proclin 300.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.
  • 抗原

    PDCD1LG2 (Programmed Cell Death 1 Ligand 2 (PDCD1LG2))

    别名

    PD-L2

    背景

    CD273, B7-DC, PDL2, B7DC, programmed death ligand 2, CD273, Pdcd1lg2

    UniProt

    Q9WUL5
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