Recombinant FOLR2 抗体
Quick Overview for Recombinant FOLR2 抗体 (ABIN7072338)
抗原
See all FOLR2 抗体抗体类型
适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- Anti-Folate receptor beta [CL10], Rat IgG2a, kappa
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产品特性
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Original Species of Ab: Rat
Original Format of Ab: IgG2a
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纯化方法
- Protein A affinity purified
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免疫原
- FRbeta -transfected RBL2H3 cells.
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亚型
- IgG2a kappa
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anti-Folate Receptor 2 (Fetal) (FOLR2) (AA 18-46) antibody
FOLR2 适用: 人, 小鼠 WB, FACS, IHC (p) 宿主: 兔 Polyclonal RB24013 unconjugated
anti-Folate Receptor 2 (Fetal) (FOLR2) antibodyFOLR2 适用: 人 WB, IHC, IHC (p), IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Folate Receptor 2 (Fetal) (FOLR2) (AA 35-167) antibodyFOLR2 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Folate Receptor 2 (Fetal) (FOLR2) (AA 36-128) antibodyFOLR2 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 4B12 unconjugated
anti-Folate Receptor 2 (Fetal) (FOLR2) antibodyFOLR2 适用: 人 WB, FACS, IP, ICC 宿主: 小鼠 Monoclonal EM-35 unconjugated
anti-Folate Receptor 2 (Fetal) (FOLR2) antibody (PE)FOLR2 适用: 人 FACS 宿主: 小鼠 Monoclonal EM-35 PE
anti-Folate Receptor 2 (Fetal) (FOLR2) antibodyFOLR2 适用: 人 WB 宿主: 小鼠 Monoclonal 1905CT501-41-76 unconjugated
anti-Folate Receptor 2 (Fetal) (FOLR2) (Internal Region) antibodyFOLR2 适用: 人, 小鼠 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Folate Receptor 2 (Fetal) (FOLR2) antibodyFOLR2 适用: 人 FACS 宿主: 兔 Chimeric unconjugated Fc fragment
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应用备注
- The antibody binds specifically to FRβ, a member of the folate receptor family. The receptor binds with high affinity to folic acid and folic acid derivatives, and transports 5-methyltetrahydrofolate into the cell. The receptor is expressed on the surface of tumour associated macrophages (TAMs) that promote growth and metastasis of tumours such as gliomas and colon, breast and lung carcinomas. Research has shown FRβ is only expressed on activated macrophages, and thereby a monoclonal antibody that targets the receptor can be useful in the diagnosis of the cancer. Furthermore, the antibody may be conjugated with a toxin, delivering the drug only to TAMs and not to healthy macrophages.
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限制
- 仅限研究用
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浓度
- 1 mg/mL
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缓冲液
- PBS with 0.02 % Proclin 300.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.
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- FOLR2 (Folate Receptor 2 (Fetal) (FOLR2))
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别名
- Folate receptor beta
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背景
- FRβ, Folate receptor 2, Folate-binding protein 2.
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UniProt
- Q05685
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途径
- Dicarboxylic Acid Transport
抗原
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