Recombinant PRNP 抗体
Quick Overview for Recombinant PRNP 抗体 (ABIN7072335)
抗原
See all PRNP 抗体抗体类型
适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- Anti-Prion [3F4], Mouse IgG1, kappa
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交叉反应
- 人
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产品特性
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Original Species of Ab: Mouse
Original Format of Ab: IgG2a
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纯化方法
- Protein A affinity purified
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免疫原
- Hamster 263K PrPs.
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亚型
- IgG1 kappa
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anti-Prion Protein (PRNP) (AA 23-230) antibody
PRNP 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Prion Protein (PRNP) (AA 23-230) antibodyPRNP 适用: 人 ELISA, FACS 宿主: 小鼠 Monoclonal 3G10G9 unconjugated
anti-Prion Protein (PRNP) antibodyPRNP 适用: 人, 大鼠, 小鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Prion Protein (PRNP) antibodyPRNP 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Prion Protein (PRNP) (AA 23-230) antibodyPRNP 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Prion Protein (PRNP) (AA 23-64) antibodyPRNP 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Prion Protein (PRNP) antibodyPRNP 适用: 人, 大鼠, 小鼠 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Prion Protein (PRNP) (Prion) antibodyPRNP 适用: 人 WB 宿主: 小鼠 Monoclonal EM-20 unconjugated
anti-Prion Protein (PRNP) (AA 143-230) antibodyPRNP 适用: 人, 大鼠, 小鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Prion Protein (PRNP) antibodyPRNP 适用: 绵羊 IHC (p), EIA 宿主: 小鼠 Monoclonal 2G11 unconjugated
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应用备注
- The antibody binds specifically to prion, a misfolded protein that has the ability to enter healthy organisms and cause other misfolding of other proteins into their prion form. This plays an essential role in the pathogenesis of certain neurodegenerative disorders such as Creutzfeldt-Jakob disease (CJD), Gerstmann-Staussler syndrome (GSS) and bovine spongiform encephalopathy (BSE). These disorders are characterised by an accumulation of prion proteins in the brain, which have a disrupted secondary structure.
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说明
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This reformatted mouse antibody was made using the variable domain sequences of the original Mouse IgG2a format, for improved compatibility with existing reagents, assays and techniques.
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限制
- 仅限研究用
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浓度
- 1 mg/mL
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缓冲液
- PBS with 0.02 % Proclin 300.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.
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- PRNP (Prion Protein (PRNP))
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别名
- Prion
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背景
- Major prion protein, p27-30, CD30 antigen, prion protein PrP, prion-related protein
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途径
- Transition Metal Ion Homeostasis, Activated T Cell Proliferation
抗原
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