Recombinant G Protein-Coupled Receptor 119 抗体
Quick Overview for Recombinant G Protein-Coupled Receptor 119 抗体 (ABIN7072310)
抗原
See all G Protein-Coupled Receptor 119 (GPR119) 抗体抗体类型
适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- Anti-Glucose-dependent insulinotropic Receptor [Gipg013], Mouse IgG2a, lambda
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特异性
- The original has a Ki value of 7 nM and a Kd value of 6.8 nM for human GIPr.
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交叉反应
- 犬, 小鼠, 大鼠
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产品特性
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Original Species of Ab: Mouse
Original Format of Ab: scFv
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纯化方法
- Protein A affinity purified
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免疫原
- Human GIPr.
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亚型
- IgG2a lambda
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anti-G Protein-Coupled Receptor 119 (GPR119) (Cytoplasmic Domain) antibody
GPR119 适用: 人, Bat IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-G Protein-Coupled Receptor 119 (GPR119) (Internal Region) antibodyGPR119 适用: 人 WB, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-G Protein-Coupled Receptor 119 (GPR119) antibodyGPR119 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-G Protein-Coupled Receptor 119 (GPR119) (Cytoplasmic Domain) antibodyGPR119 适用: 人 IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-G Protein-Coupled Receptor 119 (GPR119) (Internal Region) antibodyGPR119 适用: 人, 小鼠 WB, ELISA, IF, IHC, ICC 宿主: 兔 Polyclonal unconjugated
anti-G Protein-Coupled Receptor 119 (GPR119) (Center) antibodyGPR119 适用: 人, 猴 WB, IF, IHC, IC 宿主: 兔 Polyclonal unconjugated
anti-G Protein-Coupled Receptor 119 (GPR119) (AA 186-235) antibodyGPR119 适用: 人 WB, ELISA, IF, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-G Protein-Coupled Receptor 119 (GPR119) (C-Term) antibodyVerified GPR119 适用: 人 WB, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-G Protein-Coupled Receptor 119 (GPR119) antibodyGPR119 适用: 人, 小鼠, 大鼠, 犬 ELISA, IF, BP 宿主: 兔 Chimeric Gipg013 unconjugated Recombinant Antibody
anti-G Protein-Coupled Receptor 119 (GPR119) (AA 186-235) antibodyGPR119 适用: 人 WB, ELISA, IF 宿主: 兔 Polyclonal unconjugated
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应用备注
- This antibody binds to GIPr, a GPCR expressed on pancreatic beta-cells, where activation leads to the release of insulin. Endogeonous ligands for the receptor include oleylethanolamide and lysophosphatidylcholine. The antibody acts as a competitive antagonist. In rat islets, the antibody inhibits GIP-induced secretion of insulin by up to 81 % .
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说明
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This full-length, reformatted mouse antibody was made using the variable domain sequences of the original Mouse scFv format, for improved compatibility with existing reagents, assays and techniques.
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限制
- 仅限研究用
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浓度
- 1 mg/mL
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缓冲液
- PBS with 0.02 % Proclin 300.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.
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- G Protein-Coupled Receptor 119 (GPR119)
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别名
- Glucose-dependent insulinotropic Receptor
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背景
- GIPr
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UniProt
- Q8TDV5
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途径
- Hormone Transport, Peptide Hormone Metabolism
抗原
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