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Recombinant IL-2 抗体

This anti-IL-2 antibody is a 小鼠 单克隆 antibody detecting IL-2 in WB, ELISA, FACS, IF, Crys 和 LA. Suitable for 人.
产品编号 ABIN7072226
发货至: 中国

Quick Overview for Recombinant IL-2 抗体 (ABIN7072226)

抗原

See all IL-2 (IL2) 抗体
IL-2 (IL2) (Interleukin 2 (IL2))

抗体类型

Recombinant Antibody

适用

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宿主

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小鼠

克隆类型

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单克隆

标记

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This IL-2 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Flow Cytometry (FACS), Immunofluorescence (IF), Crystallization (Crys), Latex Agglutination (LA)

克隆位点

LNKB-2
  • 原理

    Anti-IL-2 [LNKB-2], Mouse IgG1, kappa

    特异性

    This antibody binds human IL-2 at the 59-72 site of the IL-2 sequence.

    产品特性

    Original Species of Ab: Mouse

    Original Format of Ab: IgG1

    纯化方法

    Protein A affinity purified

    亚型

    IgG1 kappa
  • 应用备注

    This antibody was quantified by ELISA and used for latex-agglutination analysis of human IL-2. It was measured to bind human IL-2 with high affinity (Ka ~ 3 x 108 M-1) (Lunev et al., 1990, PMID: 1718463). This antibody has been used successfully for WB and FACS (Stratieva-Taneeva et al., 1993, PMID: 8359822). The crystal structure characterization of the Fab version of this antibody was performed (Fokin et al., 2000, PMID: 11040993). Further crystallization of the Fab version of this antibody with an antigenic peptide revealed that the antibody-antigen complexation involves a significant rearrangement of the epitope-containing region of the IL-2 with retention of the α-helical character of the epitope fragment (Afonin et al., 2001, PMID: 11468348).

    限制

    仅限研究用
  • 浓度

    1 mg/mL

    缓冲液

    PBS with 0.02 % Proclin 300.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.
  • 抗原

    IL-2 (IL2) (Interleukin 2 (IL2))

    别名

    IL-2

    背景

    Interleukin 2, LNKB2

    UniProt

    P60568

    途径

    JAK/STAT Signaling, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Activated T Cell Proliferation
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