ZACN 抗体 (Extracellular, N-Term)
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Quick Overview for ZACN 抗体 (Extracellular, N-Term) (ABIN7043880)
抗原
See all ZACN 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 157-170, Extracellular, N-Term
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原理
- A Rabbit Polyclonal Antibody to Zinc-Activated Ion Channel
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预测反应
- Human
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产品特性
- Anti-Human ZACN (extracellular) Antibody (ABIN7043880 and ABIN7045343) is a highly specific antibody directed against an epitope of the human Zinc-activated ligand-gated ion channel. The antibody can be used in western blot, immunocytochemistry, and indirect flow cytometry applications. The antibody recognizes an extracellular epitope, and is thus ideal for detecting ZAC in living cells. It has been designed to recognize ZAC from human samples only.
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纯化方法
- Affinity purified on immobilized antigen.
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免疫原
- CNFELLHFPRDHSN, corresponding to amino acid residues 157-170 of human ZACN
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亚型
- IgG
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anti-Zinc Activated Ligand-Gated Ion Channel (ZACN) (AA 331-360), (C-Term) antibody
ZACN 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB26010 unconjugated
anti-Zinc Activated Ligand-Gated Ion Channel (ZACN) (AA 35-84) antibodyZACN 适用: 人, Cow, 犬, Pig WB 宿主: 兔 Polyclonal unconjugated
anti-Zinc Activated Ligand-Gated Ion Channel (ZACN) (N-Term) antibodyZACN 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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WB: 1:200
FC: 5 mg per reaction
ICC: 1:25
IHC: The optimal concentration should be determined by the user
IP: The optimal concentration should be determined by the user
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- 50 μL or 0.2 mL double distilled water (DDW), depending on the sample size.
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浓度
- 0.8 mg/mL
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缓冲液
- PBS pH 7.4, 1 % BSA with 0.05 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- The antibody ships as a lyophilized powder at room temperature. Upon arrival, it should be stored at -20°C
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- ZACN (Zinc Activated Ligand-Gated Ion Channel (ZACN))
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别名
- ZACN
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背景
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Synonyms: Zinc-activated ligand-gated ion channel, Ligand-gated ion channel zinc-activated 1, Ligand-gated ion-channel receptor L2, ZAC, LGICZ1
Description: Over forty homologous proteins belong to the superfamily of ligand-gated ion channels. These members are divided into subfamilies, for example: acetylcholine, serotonin and glycine receptors.A new member has been added to this superfamily - ZAC (Zinc-activated channel) which is expressed in humans and dogs but not in rodents1. Like all other ligand-gated ion channels, ZAC has four transmembrane domains and extracellular N- and C-termini. As its name states, the channel is activated by high concentrations of zinc.ZAC mRNA was found to be expressed in the placenta, spinal cord, stomach, and fetal brain1. In another study, ZAC was identified using a computer-assisted program and was detected in similar areas (including pancreas and kidney), but also displayed minor discrepancies2.Being that the channel is expressed in human and dog, deciphering its cellular/physiological functions will be challenging.
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基因ID
- 353174
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NCBI登录号
- NM_180990
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UniProt
- Q401N2
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途径
- Synaptic Membrane
抗原
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