ZACN 抗体 (Extracellular)
Quick Overview for ZACN 抗体 (Extracellular) (ABIN7043880)
抗原
See all ZACN 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 157-170, Extracellular
-
原理
- A Rabbit Polyclonal Antibody to Zinc-Activated Ion Channel
-
特异性
- Extracellular, N-terminus
-
预测反应
- Human
-
产品特性
- Anti-Human ZACN (extracellular) Antibody (ABIN7043880 and ABIN7045343) is a highly specific antibody directed against an epitope of the human Zinc-activated ligand-gated ion channel. The antibody can be used in western blot, immunocytochemistry, and indirect flow cytometry applications. The antibody recognizes an extracellular epitope, and is thus ideal for detecting ZAC in living cells. It has been designed to recognize ZAC from human samples only.
-
纯化方法
- Affinity purified on immobilized antigen.
-
免疫原
-
Immunogen: Synthetic peptide
Immunogen Sequence: CNFELLHFPRDHSN, corresponding to amino acid residues 157-170 of human ZACN
-
亚型
- IgG
-
-
anti-Zinc Activated Ligand-Gated Ion Channel (ZACN) (AA 35-84) antibody
ZACN 适用: 人, Cow, 犬, Pig WB 宿主: 兔 Polyclonal unconjugated
anti-Zinc Activated Ligand-Gated Ion Channel (ZACN) (N-Term) antibodyZACN 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Zinc Activated Ligand-Gated Ion Channel (ZACN) (AA 331-360), (C-Term) antibodyZACN 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB26010 unconjugated
-
-
应用备注
-
Antigen preadsorption control: 1 μg peptide per 1 μg antibody
Application Dilutions Immunohistochemistry paraffin embedded sections ihc: N/A
Application Dilutions Western blot wb: 1:200
-
限制
- 仅限研究用
-
-
-
状态
- Lyophilized
-
溶解方式
- Recosntitute with double distilled water (DDW) to a concentration of 1.0 mg/mL.
-
浓度
- 1 mg/mL
-
缓冲液
- PBS pH 7.4
-
储存条件
- 4 °C,-20 °C
-
储存方法
-
Storage before reconstitution: The antibody ships as a lyophilized powder at room temperature. Upon arrival, it should be stored at -20°C.
Storage after reconstitution: The reconstituted solution can be stored at 4°C for up to 1 week. For longer periods, small aliquots should be stored at -20°C. Avoid multiple freezing and thawing. Centrifuge all antibody preparations before use (10000 x g 5 min).
-
-
- ZACN (Zinc Activated Ligand-Gated Ion Channel (ZACN))
-
别名
- ZACN
-
背景
-
Zinc-activated ligand-gated ion channel, Ligand-gated ion channel zinc-activated 1, Ligand-gated ion-channel receptor L2, ZAC, LGICZ1,Over forty homologous proteins belong to the superfamily of ligand-gated ion channels. These members are divided into subfamilies, for example: acetylcholine, serotonin and glycine receptors.A new member has been added to this superfamily - ZAC (Zinc-activated channel) which is expressed in humans and dogs but not in rodents1. Like all other ligand-gated ion channels, ZAC has four transmembrane domains and extracellular N- and C-termini. As its name states, the channel is activated by high concentrations of zinc.ZAC mRNA was found to be expressed in the placenta, spinal cord, stomach, and fetal brain1. In another study, ZAC was identified using a computer-assisted program and was detected in similar areas (including pancreas and kidney), but also displayed minor discrepancies2.Being that the channel is expressed in human and dog, deciphering its cellular/physiological functions will be challenging.
Alternative names: ZACN, Zinc-activated ligand-gated ion channel, Ligand-gated ion channel zinc-activated 1, Ligand-gated ion-channel receptor L2, ZAC, LGICZ1 -
基因ID
- 353174
-
NCBI登录号
- NM_180990
-
UniProt
- Q401N2
-
途径
- Synaptic Membrane
抗原
-
