TRPV5 抗体 (Intracellular)
Quick Overview for TRPV5 抗体 (Intracellular) (ABIN7043855)
抗原
See all TRPV5 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 715-729, Intracellular
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原理
- A Rabbit Polyclonal Antibody to TRPV5 Channel
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特异性
- Intracellular, C-terminus
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交叉反应
- 人, 小鼠, 大鼠
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预测反应
- rabbit - 13,Rat - 11,15 amino acid residues identical
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产品特性
- Anti-TRPV5 Antibody is directed against an epitope of human TRPV5. Anti-TRPV5 Antibody (ABIN7043855, ABIN7043996 and ABIN7043997) can be used in western blot, immunocytochemistry and immunohistochemistry applications. It has been designed to recognize TRPV5 from human, mouse and rat samples.
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纯化方法
- Affinity purified on immobilized antigen.
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免疫原
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Immunogen: Synthetic peptide
Immunogen Sequence: (C)GLNLSEGDGEEVYHF, corresponding to amino acid residues 715-729 of human TRPV5
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亚型
- IgG
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anti-Transient Receptor Potential Cation Channel, Subfamily V, Member 5 (TRPV5) (N-Term) antibody
TRPV5 适用: 人, 大鼠, 小鼠, Cow, 犬, Pig, 豚鼠, 马, 兔 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Transient Receptor Potential Cation Channel, Subfamily V, Member 5 (TRPV5) (AA 1-100) antibodyTRPV5 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 2A6 unconjugated
anti-Transient Receptor Potential Cation Channel, Subfamily V, Member 5 (TRPV5) antibodyTRPV5 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Transient Receptor Potential Cation Channel, Subfamily V, Member 5 (TRPV5) (Internal Region) antibodyVerified TRPV5 适用: 人 WB, ELISA, IF, ICC 宿主: 山羊 Polyclonal unconjugated
anti-Transient Receptor Potential Cation Channel, Subfamily V, Member 5 (TRPV5) (AA 1-100) antibodyTRPV5 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 6D6 unconjugated
anti-Transient Receptor Potential Cation Channel, Subfamily V, Member 5 (TRPV5) (AA 1-100) antibodyTRPV5 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Transient Receptor Potential Cation Channel, Subfamily V, Member 5 (TRPV5) (Internal Region) antibody (Biotin)Verified TRPV5 适用: 人 WB, ELISA, IF, ICC 宿主: 山羊 Polyclonal Biotin
anti-Transient Receptor Potential Cation Channel, Subfamily V, Member 5 (TRPV5) antibodyTRPV5 适用: 大鼠 IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Transient Receptor Potential Cation Channel, Subfamily V, Member 5 (TRPV5) (AA 38-87) antibodyTRPV5 适用: 人, 大鼠, 小鼠, Cow, 犬, 豚鼠, 马, 兔 WB 宿主: 兔 Polyclonal unconjugated
anti-Transient Receptor Potential Cation Channel, Subfamily V, Member 5 (TRPV5) (AA 1-325) antibodyTRPV5 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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Antigen preadsorption control: 1 μg peptide per 1 μg antibody
Application Dilutions Immunohistochemistry paraffin embedded sections ihc: 1:100
Application Dilutions Western blot wb: 1:200
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说明
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Cited Application: ICC|IFC
Negative Control: (ABIN7237501)
Blocking Peptide: (ABIN7237501)
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- 0.2 mL double distilled water (DDW).
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浓度
- 1 mg/mL
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缓冲液
- PBS pH 7.4
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储存条件
- 4 °C,-20 °C
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储存方法
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Storage before reconstitution: The antibody ships as a lyophilized powder at room temperature. Upon arrival, it should be stored at -20°C.
Storage after reconstitution: The reconstituted solution can be stored at 4°C for up to 1 week. For longer periods, small aliquots should be stored at -20°C. Avoid multiple freezing and thawing. Centrifuge all antibody preparations before use (10000 x g 5 min).
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- TRPV5 (Transient Receptor Potential Cation Channel, Subfamily V, Member 5 (TRPV5))
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别名
- TRPV5
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背景
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Transient receptor potential cation channel subfamily V member 5, Calcium transport protein 2, CaT2, Epithelial calcium channel 1, ECaC1, OTRPC3,TRP channels are a large family (about 28 genes) of plasma membrane, non-selective cationic channels that are either specifically or ubiquitously expressed in excitable and non-excitable cells.1 According to IUPHAR, the TRP family is comprised of three main subfamilies on the basis of sequence homology, TRPC, TRPM and TRPV (to date, three extra subfamilies are considered to belong to the TRP family, the TRPA, TRPML, and TRPP).1-4 The TRPV subfamily consists of six members, TRPV1-6.5TRPV5 (ECaC) and TRPV6 (CaT1) are unique members of the TRP family. Both are epithelial Ca2+ channels, form constitutively open channels, share high degree of homology (about 66 % ) with differences in the N- and C-terminus. TRPV6 and TRPV5 are expressed in a 1,25-dihydroxyvitamin D3 dependent manner. In contrast to other members of the TRP family, TRPV5 and TRPV6 are highly Ca2+ selective and are expressed in Ca2+ transporting epithelia where they are assumed to have an important role in Ca2+ reabsorption.6,7 TRPV5 is preferentially expressed in the kidney.
Alternative names: TRPV5, Transient receptor potential cation channel subfamily V member 5, Calcium transport protein 2, CaT2, Epithelial calcium channel 1, ECaC1, OTRPC3 -
基因ID
- 56302
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NCBI登录号
- NM_019841
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UniProt
- Q8NDW5
抗原
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