TBXA2R 抗体 (AA 225-239)
Quick Overview for TBXA2R 抗体 (AA 225-239) (ABIN7043809)
抗原
See all TBXA2R 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 225-239
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原理
- A Rabbit Polyclonal Antibody to Thromboxane A2 Receptor
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特异性
- 3rd intracellular loop
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交叉反应
- 人, 小鼠, 大鼠
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预测反应
- Rat - 14,15 amino acid residues identical, human - 12, mouse - 13
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产品特性
- Anti-Thromboxane A2 Receptor Antibody (ABIN7043809, ABIN7045124 and ABIN7045125) is a highly specific antibody directed against an epitope of the rat TBXA2R. The antibody can be used in western blot and immunohistochemistry applications. It has been designed to recognize TBXA2R from rat, mouse, and human samples.
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纯化方法
- Affinity purified on immobilized antigen.
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免疫原
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Immunogen: Synthetic peptide
Immunogen Sequence: (C)HAREATQRPRD(S)EVE, corresponding to amino acid residues 225-239 of rat TBXA2R
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亚型
- IgG
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anti-Thromboxane A2 Receptor (TBXA2R) (AA 3-324) antibody
TBXA2R 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Thromboxane A2 Receptor (TBXA2R) (AA 51-150) antibodyTBXA2R 适用: 人, 小鼠 ELISA, FACS, IF (cc), IF (p), ICC, IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Thromboxane A2 Receptor (TBXA2R) (C-Term) antibodyTBXA2R 适用: 人 IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Thromboxane A2 Receptor (TBXA2R) (AA 13-27), (Extracellular) antibodyTBXA2R 适用: 人 WB, FACS, LCI 宿主: 兔 Polyclonal unconjugated
anti-Thromboxane A2 Receptor (TBXA2R) (C-Term) antibodyTBXA2R 适用: 人, 小鼠, 大鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Thromboxane A2 Receptor (TBXA2R) (Cytoplasmic Domain) antibodyTBXA2R 适用: 人 IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Thromboxane A2 Receptor (TBXA2R) (C-Term) antibodyVerified TBXA2R 适用: 人 WB, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-Thromboxane A2 Receptor (TBXA2R) (AA 323-343) antibodyTBXA2R 适用: 人 WB, ICC 宿主: 兔 Polyclonal unconjugated
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应用备注
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Antigen preadsorption control: 1 μg peptide per 1 μg antibody
Application Dilutions Immunohistochemistry paraffin embedded sections ihc: 1:200
Application Dilutions Western blot wb: 1:200
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说明
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Negative Control: (ABIN7237385)
Blocking Peptide: (ABIN7237385)
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- 0.2 mL double distilled water (DDW).
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浓度
- 1 mg/mL
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缓冲液
- PBS pH 7.4
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储存条件
- 4 °C,-20 °C
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储存方法
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Storage before reconstitution: The antibody ships as a lyophilized powder at room temperature. Upon arrival, it should be stored at -20°C.
Storage after reconstitution: The reconstituted solution can be stored at 4°C for up to 1 week. For longer periods, small aliquots should be stored at -20°C. Avoid multiple freezing and thawing. Centrifuge all antibody preparations before use (10000 x g 5 min).
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- TBXA2R (Thromboxane A2 Receptor (TBXA2R))
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别名
- TBXA2R
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背景
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Prostanoid TP receptor, TXA2-R, TBXA2R,Thromboxane A2 (TxA2) is a prostanoid that is synthesized from arachidonic acid and plays an important role in haemostasis, a process regulating platelet aggregation and vascular tone. Thromboxane A2 binds to the thromboxane A2 receptor (TBXA2R) to induce strong vasoconstriction in renal arteries.Thromboxane A2 receptor is a seven-transmembrane G-protein coupled receptor localized on the cell membrane and in intracellular compartments. TBXA2R is expressed in the central nervous system in several types of cells, such as microglia, oligodendrocytes and astrocytes. Imbalances in the levels of the receptor is widely implicated in several cardiovascular, pulmonary, renal and prostate pathologies1-3.Thromboxane A2 receptor mediates vasoconstriction and ischemia and its activation is implicated in atherosclerosis and inflammation. Activation of the receptor induces endothelial cell apoptosis by inhibiting Akt phosphorylation and also inhibits endothelial cell migration and angiogenesis by decreasing Akt and eNOS phosphorylation1-3.
Alternative names: Thromboxane A2 Receptor, Prostanoid TP receptor, TXA2-R, TBXA2R -
基因ID
- 24816
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NCBI登录号
- NM_001060
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UniProt
- P34978
抗原
-
