TBXA2R 抗体 (Extracellular, N-Term)
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Quick Overview for TBXA2R 抗体 (Extracellular, N-Term) (ABIN7043808)
抗原
See all TBXA2R 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 13-27, Extracellular, N-Term
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原理
- A Rabbit Polyclonal antibody to Thromboxane A2 Receptor (extracellular).
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交叉反应
- 人, 小鼠, 大鼠
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预测反应
- Mouse,rat - 12 out of 15 amino acid residues identical
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产品特性
- A rabbit polyclonal antibody to Thromboxane A2 Receptor (extracellular).
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纯化方法
- Affinity purified on immobilized antigen.
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免疫原
- (C)RPTNITLEERRLIAS, corresponding to amino acid residues 13 - 27 of human TBXA2R
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亚型
- IgG
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anti-Thromboxane A2 Receptor (TBXA2R) (AA 3-324) antibody
TBXA2R 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Thromboxane A2 Receptor (TBXA2R) (AA 51-150) antibodyTBXA2R 适用: 人, 小鼠 ELISA, FACS, IF (cc), IF (p), ICC, IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Thromboxane A2 Receptor (TBXA2R) (C-Term) antibodyTBXA2R 适用: 人 IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Thromboxane A2 Receptor (TBXA2R) (3rd Intracellular Loop), (AA 225-239) antibodyTBXA2R 适用: 大鼠 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Thromboxane A2 Receptor (TBXA2R) (C-Term) antibodyVerified TBXA2R 适用: 人 WB, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-Thromboxane A2 Receptor (TBXA2R) (C-Term) antibodyTBXA2R 适用: 人, 小鼠, 大鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Thromboxane A2 Receptor (TBXA2R) (Cytoplasmic Domain) antibodyTBXA2R 适用: 人 IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Thromboxane A2 Receptor (TBXA2R) (AA 323-343) antibodyTBXA2R 适用: 人 WB, ICC 宿主: 兔 Polyclonal unconjugated
anti-Thromboxane A2 Receptor (TBXA2R) antibodyTBXA2R 适用: 人 WB 宿主: 兔 Monoclonal 24GB1845 unconjugated Recombinant Antibody
anti-Thromboxane A2 Receptor (TBXA2R) (AA 13-27), (Extracellular), (N-Term) antibody (FITC)TBXA2R 适用: 人 FACS, LCI 宿主: 兔 Polyclonal FITC
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应用备注
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WB: 1:200
FC: 2.5 μg per reaction
ICC: The optimal concentration should be determined by the user
IHC: The optimal concentration should be determined by the user
IP: The optimal concentration should be determined by the user
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说明
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Negative Control: (ABIN7237389)
Blocking Peptide: (ABIN7237389)
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- 25 μL, 50 μL or 0.2 mL double distilled water (DDW), depending on the sample size.
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浓度
- 0.8 mg/mL
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缓冲液
- PBS pH 7.4, 1 % BSA with 0.05 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- The antibody ships as a lyophilized powder at room temperature. Upon arrival, it should be stored at -20°C
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- TBXA2R (Thromboxane A2 Receptor (TBXA2R))
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别名
- TBXA2R
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背景
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Synonyms: Prostanoid TP receptor, TXA2-R, TBXA2R
Description: Thromboxane A2 (TxA2) is a prostanoid that is synthesized from arachidonic acid and plays an important role in haemostasis, a process regulating platelet aggregation and vascular tone. Thromboxane A2 binds to the thromboxane A2 receptor (TBXA2R) to induce strong vasoconstriction in renal arteries.Thromboxane A2 receptor is a seven-transmembrane G-protein coupled receptor localized on the cell membrane and in intracellular compartments. TBXA2R is expressed in the central nervous system in several types of cells, such as microglia, oligodendrocytes and astrocytes. Imbalances in the levels of the receptor is widely implicated in several cardiovascular, pulmonary, renal and prostate pathologies1-3.Thromboxane A2 receptor mediates vasoconstriction and ischemia and its activation is implicated in atherosclerosis and inflammation. Activation of the receptor induces endothelial cell apoptosis by inhibiting Akt phosphorylation and also inhibits endothelial cell migration and angiogenesis by decreasing Akt and eNOS phosphorylation1-3.
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基因ID
- 6915
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NCBI登录号
- NM_001060
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UniProt
- P21731
抗原
-
