Syntaxin 4 抗体 (Intracellular, N-Term)
Our Local Distributor
北京 101111
Quick Overview for Syntaxin 4 抗体 (Intracellular, N-Term) (ABIN7043796)
抗原
See all Syntaxin 4 (STX4) 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 2-23, Intracellular, N-Term
-
原理
- A Rabbit Polyclonal Antibody to Syntaxin 4
-
交叉反应
- 小鼠, 大鼠
-
预测反应
- Mouse - identical, human - 17,22 amino acid residues identical
-
产品特性
- Anti-Syntaxin 4 Antibody is directed against an epitope of rat Syntaxin 4. Anti-Syntaxin 4 Antibody (ABIN7043796, ABIN7044650 and ABIN7044651) can be used in western blot and immunohistochemical applications. It was designed to recognize Syntaxin 4 from rat, mouse and human samples.
-
纯化方法
- Affinity purified on immobilized antigen.
-
免疫原
- RDRTHELRQGDNISDDEDEVRV(C), corresponding to residues 2-23 of rat syntaxin 4
-
亚型
- IgG
-
-
anti-Syntaxin 4 (STX4) (AA 19-119) antibody
STX4 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 6A1 unconjugated
anti-Syntaxin 4 (STX4) (AA 1-297) antibodySTX4 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Syntaxin 4 (STX4) antibodySTX4 适用: 人 WB, IF 宿主: 兔 Monoclonal unconjugated
anti-Syntaxin 4 (STX4) antibodyKD Validated STX4 适用: 人 WB, FACS 宿主: 兔 Monoclonal 25GB3340 unconjugated Recombinant Antibody
anti-Syntaxin 4 (STX4) (AA 1-297) antibodySTX4 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Syntaxin 4 (STX4) (AA 101-150) antibodySTX4 适用: 人, 大鼠, 小鼠, Cow, Pig, 兔, 猴, 马, Bat WB 宿主: 兔 Polyclonal unconjugated
anti-Syntaxin 4 (STX4) (C-Term) antibodySTX4 适用: 人, Cow, Pig, 兔, 犬, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-Syntaxin 4 (STX4) (AA 1-273) antibodySTX4 适用: 大鼠, 小鼠 WB, IP, ICC 宿主: 小鼠 Monoclonal 139-2 unconjugated
anti-Syntaxin 4 (STX4) (AA 1-273) antibodySTX4 适用: 人, 大鼠, 小鼠, Hamster WB, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Syntaxin 4 (STX4) (C-Term) antibodySTX4 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
-
-
应用备注
-
WB: 1:400
FC: The optimal concentration should be determined by the user
ICC: The optimal concentration should be determined by the user
IHC: 1:100
IP: The optimal concentration should be determined by the user
-
说明
-
Negative Control: (ABIN7237347)
Blocking Peptide: (ABIN7237347)
-
限制
- 仅限研究用
-
-
-
状态
- Lyophilized
-
溶解方式
- 25 μL, 50 μL or 0.2 mL double distilled water (DDW), depending on the sample size.
-
浓度
- 0.8 mg/mL
-
缓冲液
- PBS pH 7.4, 1 % BSA with 0.05 % sodium azide
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- -20 °C
-
储存方法
- The antibody ships as a lyophilized powder at room temperature. Upon arrival, it should be stored at -20°C
-
-
- Syntaxin 4 (STX4)
-
别名
- STX4
-
背景
-
Synonyms: STX4, Renal carcinoma antigen NY-REN-31, P35-2
Description: Syntaxin 4 is a member of the soluble N-ethylmaleimide-sensitive factor attachment protein receptor (SNARE) protein superfamily. The family includes 36 members in humans and is characterized by the SNARE motif, an evolutionarily conserved stretch of 60-70 amino acids that are arranged in heptad repeats1,2.SNARE proteins are involved in exocytosis and intracellular vesicle trafficking and are essential for cell growth, hormone secretion and neurotransmission, processes that require rapid, targeted, and regulated membrane fusion1,2.SNAREs can be roughly divided into vesicular (v-SNAREs) and target (t-SNAREs) based on their distribution on the transport vesicle or target membrane respectively. Thus, assembly of cognate v-/t-SNAREs between two opposing membranes generates trans-SNARE complexes, which bring the lipid bilayers in close proximity and drive membrane fusion.Syntaxin 4, like most SNAREs, is a type IV membrane protein with a relatively large N-terminus containing the SNARE motif located in the cytoplasmic side and a transmembrane domain located close to the C-terminus that functions as an anchor1,2.Syntaxin 4 functions as a plasma membrane protein t-SNARE and has been shown to have an important role in pancreatic b-cell insulin secretion and in insulin-stimulated glucose uptake in skeletal muscle and adipose tissue by means of translocation of the glucose transporter GLUT4 from an intracellular compartment to the plasma membrane3,4.
-
基因ID
- 81803
-
NCBI登录号
- NM_004604
-
UniProt
- Q08850
-
途径
- Synaptic Vesicle Exocytosis
抗原
-
